You Searched For: Genscript

Catalog Number: (89493-878)

Supplier: Genscript

Description: Bmp-7, Or Osteogenic Protein 1 (Op-1) It Is One Of At Least 15 Structurally And Functionally Related Bmps, All Members Of The Transforming Growth Factor B (Tgf-B) Superfamily. Bmps Regulate Cartilage And Bone Formation Tissues And Organs

Catalog Number: (89494-362)

Supplier: Genscript

Description: Histone Deacetylase 1 Is Responsible For The Deacetylation Of Lysine Residues On The N-Terminal Portion Of Core Histones H2A, H2B, H3, And H4. Histone Deacetylation Gives A Tag For Epigenetic Repression And Plays An Important Role In Transcriptional Regulation

Catalog Number: (89494-424)

Supplier: Genscript

Description: Htra2 (High Temperature Requirement Protein A2)/Omi Is A Serine Protease. It Is Localized At Mitochondria And Can Be Released To The Cytosol Following Apoptotic Stimulus. Htra2 Protein Induces Apoptosis By Binding.

Catalog Number: (89494-206)

Supplier: Genscript

Description: Gap-43 Is Termed As A Growth Or Plasticity Protein Because It Is Expressed At High Levels In Neuronal Growth Cones.Gap-43 Is Considered To Be A Crucial Component Associated With Effective Regenerative RespoNSE In The Nervous System.

Catalog Number: (89494-682)

Supplier: Genscript

Description: Nmt55/P54Nrb Is A Dna And Rna Binding Protein Which Participates In Multiple Cellular Functions Such As Regulation Of Cell Division As Well As Cancer Biology.

Catalog Number: (89494-934)

Supplier: Genscript

Description: SAP102 (Synapse-Associated Protein 102) Is One Member Of The Membrane-Associated Guanylate Kinase (Maguk) Protein Family. It Consists Of Three Pdz Domains, A Src Homology 3 (Sh3) Domain, And A Guanylate Kinase (Gk) Domain.

Catalog Number: (77007-472)

Supplier: Genscript

Description: Etanercept with trade name Enbrel, is an FDA-approved drug to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Etanercept is a fusion protein made from the combination of two naturally occurring soluble human 75-kilodalton TNF receptors linked to an Fc portion of an IgG1. Etanercept treats autoimmune diseases by interfering with tumor necrosis factor-alpha (TNF alpha, a soluble inflammatory cytokine) by acting as a TNF alpha inhibitor.Anti-Etanercept Antibody (4H1), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Etanercept.

Catalog Number: (77007-586)

Supplier: Genscript

Description: Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as immune checkpoint inhibition. Anti-Avelumab Antibody (12H7), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Avelumab.

Catalog Number: (77007-592)

Supplier: Genscript

Description: Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. The expression of isoform A2 (CLDN18.2) is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level). However, CLDN18.2 is highly expressed in certain primary malignant tumors, such as gastric cancer (GC), breast cancer, colon cancer and liver cancer. CLDN18.2 is expressed in 50 - 70% of primary gastric adenocarcinomas and their metastases, thus it is considered a promising candidate for targeted gastric cancer therapy. Therapeutic antibodies against Claudin 18.2 have great therapeutic potential and very low toxicity.

Catalog Number: (77007-588)

Supplier: Genscript

Description: Adeno-associated virus type 8 (AAV8) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. AAV8 empty capsids are composed of three proteins, VP1, VP2 and VP3 with relative molecular masses of 87, 72 and 62 kDa, respectively.

Catalog Number: (77007-572)

Supplier: Genscript

Description: Protein A, a bacterial cell wall protein isolated from Staphylococcus aureus, binds to mammalian IgGs mainly through Fc regions. The protein A is most commonly bound to a chromatography resin, used for production of antibody drugs or reagents. Protein A antibody can be used for quantification of protein A in sample foods or for evaluation of protein A resin. This protein A mAb is advantageous due to its IgG1 isotype, for mouse IgG1 has weak binding capacity to protein A.GenScript protein A Antibody [biotin], mAb, mouse is protein A antibody conjugated with biotin. The conjugated antibody is suitable for detecting the expression level of protein A.

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). Nucleocapsid Protein is a most abundant structure protein of the coronavirus which is associated with nucleic acid.

Catalog Number: (77007-596)

Supplier: Genscript

Description: Adeno-associated virus type 2 (AAV2) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. The AAV2 capsid (intact particle) comprises three types of subunits, VP1, VP2, and VP3, a total of 60 copies in a ratio of 1:1:8 (VP1:VP2:VP3). For the application of AAV2 vector in gene therapy, the determination of total capsid titer is essential, accurate characterization and quantification of purified AAV2 particle product represent a critical step for clinical application. GenScript Anti-AAV2 (intact particle) Antibody (2C4), mAb, Mouse is produced from cell culture <i>in vitro</i> under conditions free from animal-derived components.

Catalog Number: (76197-948)

Supplier: Genscript

Description: WB-MASTER Protein Standard, Designed for convenient protein identification in western blot, Consists of 7 recombinant proteins with MW of 20-120KDa, Volume: 2.5-10 ul/well, the loading volume of the marker should be optimized for different experiments, Size: 250ul

Catalog Number: (76197-302)

Supplier: Genscript

Description: The product is specific for Pembrolizumab. Thisantibody blocks Pembrolizumab binding with human PD-1 recombinant protein(Z03370, PD 1 Fc Chimera, Human) in ELISAs.

Catalog Number: (76197-316)

Supplier: Genscript

Description: GenScript MonoRab™ Rabbit Anti-Camelid VHH Antibody, mAb is specific for Camelid sdAb (Alpaca, Llama and Camel). The monoclonal antibody has no cross-reactivity with mouse, rat, rabbit, chicken, goat or human immunoglobulins.