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Description: Rabbit polyclonal antibody to CCT6B (N-terminal)
Catalog Number: 89267-418
Supplier: Genetex


Description: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease. [provided by RefSeq]
Catalog Number: 89357-908
Supplier: Genetex


Description: Purity: Immunogen affinity purified Species Reactivity: Human Tested Applications: ELISA, WB Pkg Size: 50 ug
Catalog Number: 89317-340
Supplier: Genetex


Description: Mouse Monoclonal antibody to PPAR alpha
Catalog Number: 10167-952
Supplier: Genetex


Description: Rabbit Polyclonal antibody to Heat Shock Protein 104
Catalog Number: 89292-274
Supplier: Genetex


Description: Rabbit polyclonal antibody to CPEB2 (N-terminal)
Catalog Number: 89270-322
Supplier: Genetex


Description: Mouse monoclonal antibody [2-35] to CD4
Catalog Number: 89265-424
Supplier: Genetex


Description: Rabbit polyclonal antibody to CRELD1 (C-terminal)
Catalog Number: 89288-564
Supplier: Genetex


Description: Rabbit Polyclonal antibody to STK32B (serine/threonine kinase 32B)
Catalog Number: 89355-000
Supplier: Genetex


Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: WB Pkg Size: 100 ul
Catalog Number: 89323-518
Supplier: Genetex


Description: Rabbit polyclonal antibody to TMEM146 (Middle)
Catalog Number: 89266-970
Supplier: Genetex


Description: Rabbit Polyclonal antibody to Cytokeratin 31 (keratin 31)
Catalog Number: 89320-986
Supplier: Genetex


Description: Rabbit Polyclonal antibody to TCTP (tumor protein, translationally-controlled 1)
Catalog Number: 89319-440
Supplier: Genetex


Description: Rabbit Polyclonal antibody to CD2 (CD2 molecule)
Catalog Number: 89318-582
Supplier: Genetex


Description: Purity: Purified by protein A chromatography or sequential differential precipitations Species Reactivity: Bacteria Tested Applications: ICC/IF, IP Pkg Size: 500 ul
Catalog Number: 89331-424
Supplier: Genetex


Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: WB Pkg Size: 100 ul
Catalog Number: 89322-834
Supplier: Genetex


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