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Catalog Number: (89359-700)
Supplier: Genetex
Description: Calnexin, also referred to as IP90, p88 and p90, is an ~90 kDa integral membrane protein of the endoplasmic reticulum (ER). Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins. Studies indicate that calnexin associates with the major histocompatability complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes. It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP 78 and GRP 94 and protein disulfide isomerase. Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention. Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).


Catalog Number: (89337-244)
Supplier: Genetex
Description: Mouse monoclonal antibody [DAXX-01] to Daxx


Catalog Number: (89363-622)
Supplier: Genetex
Description: Rabbit polyclonal antibody to HMGCS2 (N-terminal)


Catalog Number: (89284-498)
Supplier: Genetex
Description: Rat monoclonal antibody [MR5D3] to Mannose Receptor


Catalog Number: (89321-626)
Supplier: Genetex
Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: WB Pkg Size: 100 ul


Catalog Number: (89320-354)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to PDCD5 (programmed cell death 5)


Catalog Number: (89333-286)
Supplier: Genetex
Description: Validated pair of antibodies for Ferritin


Catalog Number: (89329-244)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PGCC1


Catalog Number: (89321-476)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1)


Catalog Number: (89364-858)
Supplier: Genetex
Description: Mouse monoclonal [25D5] antibody to PSMC5


Catalog Number: (89295-686)
Supplier: Genetex
Description: Goat Polyclonal antibody to PAI-1 Purity: Affinity purified by Protein G. Species Reactivity: Rabbit Tested Applications: ELISA WB Pkg Size: 500 ug


Catalog Number: (10168-914)
Supplier: Genetex
Description: Mouse Monoclonal Antibody [5G4] to HSP90AB1


Catalog Number: (89271-724)
Supplier: Genetex
Description: Mouse monoclonal antibody [2C4] to TYRO3


Catalog Number: (89358-376)
Supplier: Genetex
Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: ICC/IF, WB Pkg Size: 100 ul


Catalog Number: (89297-664)
Supplier: Genetex
Description: Goat Polyclonal antibody to DARC


Catalog Number: (89302-632)
Supplier: Genetex
Description: Rabbit polyclonal to WNT4 (Internal)


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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  • issued document with your organization's Federal Tax ID Number
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