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Description: Retinoid X receptor alpha (RXRA). Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes. This antibody is a rabbit polyclonal antibody raised against the 350 AA of human RXRA C-terminal. RXRA is highly expressed in liver, also expressed in lung, kidney and heart. It specifically recognizes the 51kd human RXRA protein.
Catalog Number: 10093-738
Supplier: Proteintech


Description: DHRS4(Dehydrogenase/reductase SDR family member 4) is also named as PHCR , NRDR ,PSCD , SCAD-SRL, and belongs to the short-chain dehydrogenases/reductases (SDR) family. It can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Human DHRS4 is a tetramer composed of 27 kDa subunits, which is inactivated at low temperature without dissociation into subunits.
Catalog Number: 10085-826
Supplier: Proteintech


Description: Stab. with 0.1% 4-methoxyphenol
Catalog Number: CAAAAL12502-03
Supplier: Thermo Scientific Chemicals

Description: 1-(5-Chloro-2-pyridinyl)piperazine 99%
Catalog Number: CAAAAH50862-MD
Supplier: Thermo Scientific Chemicals

Description: Read measurements in an unobstructed 360° view.
Catalog Number: MFLX32477-14
Supplier: VWR International


Description: Designed for labs and plant processes where multiple gases are used.
Catalog Number: MFLX68560-03
Supplier: VWR International


Description: Durable single-piece body withstands severe shock and vibration.
Catalog Number: MFLX32458-02
Supplier: VWR International


Catalog Number: CAAA46652-22
Supplier: Thermo Scientific Chemicals

Description: [Triflating Reagent]
CAS Number: 145100-51-2
MDL Number: MFCD00191833
Molecular Formula: C7H3ClF6N2O4S2
Molecular Weight: 392.67
Purity/Analysis Method: >96.0% (GC)
Form: Crystal
Catalog Number: TCB1865-25G
Supplier: TCI America

Description: Designed for labs and plant processes where multiple gases are used.
Catalog Number: MFLX68561-57
Supplier: VWR International


Description: A cell permeable, selective, and ATP-competitive inhibitor of Rho kinase (ROCK) activity (IC50=25µM). Does not inhibit the activation of Rho nor does it affect the in vitro activities of MLCK, PKCα, and SAPK2a/p38α. Shown to be less potent than Y-27632.
Catalog Number: 89147-880
Supplier: Enzo Life Sciences


Description: 3-(2-Aminoethyl)pyridine 98%
Catalog Number: CAAAAL16311-06
Supplier: Thermo Scientific Chemicals

Description: (stabilized with HQ)
CAS Number: 17435-72-2
MDL Number: MFCD00031518
Molecular Formula: C6H9BrO2
Molecular Weight: 193.04
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 86
Flash Point (°C): 81
Specific Gravity (20/20): 1.40
Storage Temperature: 0-10°C
Catalog Number: TCB1820-001G
Supplier: TCI America

Description: Stab. with 50ppm to 100ppm 4-methoxyphenol
Catalog Number: CAAAA44793-06
Supplier: Thermo Scientific Chemicals

Description: The large molecular-weight immunophilin, FKBP52, is a known target of the immunosuppressive drug FK506. FKBP52 exhibits peptidyl-prolyl cis–trans isomerase (PPIase) activity, which is inhibited by the binding of FK506—properties that it shares with the smaller but better-studied immunophilin, FKBP12. It is essential to AR-mediated induction of genes involved in sexually dimorphic development of the penis (NKX3-1), in erectile function of the mature organ (NOS2 and NOS3), and in promotion of apoptosis during development.
Catalog Number: 10087-038
Supplier: Proteintech


Description: Abiraterone Acetate, Purity: >98.0%(HPLC)(T), Cas number: 154229-18-2, Molecular Formula: C26H33NO2, Molecular Weight: 391.56, Appearance: White - Very pale yellow Solid crystal powder, Synonyms: 3B-17-(3-Pyridyl)androsta-5,16-dien-3-ol Acetate, Size: 1G
Catalog Number: TCA2891-200MG
Supplier: TCI America

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