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Image Unavailable-10162-696

Anti-HIST1H3A Rabbit Polyclonal Antibody

Description: Rabbit polyclonal antibody to H3 (acetyl Lys18)
Catalog Number: 10162-696
Supplier: Genetex
Image Unavailable-103007-988

[Lys(Ac)14]-Histone H3 (1-21)-GGK,Biotin

Description: This peptide is Histone H3 amino acid residues 1 to 21 acetylated at Lys-14 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTARKSTGG-K(Ac)-APRKQLA-GGK(Biotin)
MW:2765.3 Da
% peak area by HPLC:95
Storage condition:-20° C
Catalog Number: 103007-988
Supplier: Anaspec Inc
Product Image-10102-716

Anti-MSL2 Rabbit Polyclonal Antibody

Description: MSL2L1 is the component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure.
Catalog Number: 10102-716
Supplier: Prosci
Image Unavailable-10162-718

Anti-HIST1H3A Rabbit Polyclonal Antibody

Description: Rabbit polyclonal antibody to Histone H3R17me2K18ac (dimethyl Arg17, acetyl Lys18)
Catalog Number: 10162-718
Supplier: Genetex
Product Image-10083-672

Anti-BRD8 Mouse Monoclonal Antibody [clone: 5B6D6]

Description: BRD8 is one of the bromodomain-containing proteins, which is an acetylated lysine- binding domain and thought to be involved in regulation of protein acetylation and/or HAT (histone acetyl transferase) activity . It is also reported to be an accessory subunit of NuA4 HAT complex (also known as TRRAP/TIP60 complex) through biochemical purification . In addition, it can bind to thyroid hormone receptor-ß and/or retinoid X receptor, and can act as a coactivator of the nuclear hormone receptor-mediated transcription in reporter assays .
Catalog Number: 10083-672
Supplier: Proteintech
Image Unavailable-103007-984

[Lys(Ac)9]-Histone H3 (1-21)-GGK,Biotin

Description: This peptide is Histone H3 amino acid residues 1 to 21 acetylated at Lys-9 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTAR-K(Ac)-STGGKAPRKQLA-GGK(Biotin)
MW:2765.3 Da
% peak area by HPLC:95
Storage condition:-20° C
Catalog Number: 103007-984
Supplier: Anaspec Inc
Product Image-10087-616

Anti-HDAC8 Rabbit Polyclonal Antibody

Description: Histone deacetylases (HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 8 was primarily found in the nucleus. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. This antibody is a rabbit polyclonal antibody raised against full length HDAC8 of human origin.
Catalog Number: 10087-616
Supplier: Proteintech
Product Image-89160-284

FLUOR DE LYS® Developer I Concentrate, Enzo Life Sciences

Description: FLUOR DE LYS® Developer is an essential reagent for signal generation in HDAC or sirtuin assays done with the FLUOR DE LYS® substrate. An appropriate FLUOR DE LYS® family substrate, comprising an acetylated lysine side chain, is first incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.).
Catalog Number: 89160-284
Supplier: Enzo Life Sciences
Product Image-10101-684

Anti-DPF3 Rabbit Polyclonal Antibody

Description: DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.
Catalog Number: 10101-684
Supplier: Prosci
Image Unavailable-103007-656

[Lys(Ac)14]-Histone H3 (9-19)

Description: This is a H3 peptide acetylated at the lysine residue at the 14th position. This peptide has been shown to act as part of the active promoter state and the extent of its acetylation could be driven by cis regulatory elements such as CpG contents at promoters. It's expression has been shown to be decreased as malignancy of ovarian epithelial tumors increased, suggesting that this peptide could act as a prognostic marker although it does not show significant relation with the occurence or development of ovarian tumors.
Sequence:KSTGG-K(Ac)-APRKQ
MW:1199.4 Da
% peak area by HPLC:95
Storage condition:-20° C
Catalog Number: 103007-656
Supplier: Anaspec Inc
Product Image-10076-328

Anti-SIRT7 Rabbit Polyclonal Antibody

Description: SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Catalog Number: 10076-328
Supplier: Prosci
Image Unavailable-76764-314

Anti-pan Kac (methylated) Rabbit Polyclonal Antibody

Description: Anti-pan Kac (methylated) Rabbit Polyclonal Antibody
Catalog Number: 76764-314
Supplier: Prosci
Product Image-10062-322

Anti-DPF3 Rabbit Polyclonal Antibody

Description: The DPF3 protein, also known as Cerd4, is a member of the d4 gene family of transcription modulators that also includes DPF1/Neud4 and DPF2/Requiem. DPF3 has been shown to be a epigenetic key factor for heart and muscle development and can bind to methylated and acetylated lysine residues of histone 3 and 4, suggesting that DPF3 may play a role in recruiting chromatin remodeling complexes to acetylated histones. Two isoforms of DPF3, DPF3a and DPF3b, are required as transcriptional co-activators in SWI/SNF complex-dependent activation of the NF-kappaB RelA/p50 heterodimer.
Catalog Number: 10062-322
Supplier: Prosci
Image Unavailable-77438-234

Anti-Pan-Histone H3 Rabbit Polyclonal Antibody

Description: Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Catalog Number: 77438-234
Supplier: Bioss
Product Image-10752-090

Anti-DPF3 Rabbit Polyclonal Antibody

Description: The DPF3 protein, also known as Cerd4, is a member of the d4 gene family of transcription modulators that also includes DPF1/Neud4 and DPF2/Requiem. DPF3 has been shown to be a epigenetic key factor for heart and muscle development and can bind to methylated and acetylated lysine residues of histone 3 and 4, suggesting that DPF3 may play a role in recruiting chromatin remodeling complexes to acetylated histones. Two isoforms of DPF3, DPF3a and DPF3b, are required as transcriptional co-activators in SWI/SNF complex-dependent activation of the NF-kappaB RelA/p50 heterodimer.
Catalog Number: 10752-090
Supplier: Prosci
Product Image-10088-126

Anti-HDAC2 Rabbit Polyclonal Antibody

Description: Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin.Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). At least 4 classes of HDAC were identified. As a class I HDAC, HDAC2 was primarily found in the nucleus. HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human HDAC2 and is specific to HDAC2. It will not cross react with other HDACs.
Catalog Number: 10088-126
Supplier: Proteintech
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