You Searched For: Fmoc-O-phospho-L-tyrosine

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Anti-CBL Rabbit Polyclonal Antibody

Catalog Number: (10068-518)

Supplier: Prosci

Description: Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.

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Anti-MET Rabbit Polyclonal Antibody

Catalog Number: (10813-846)

Supplier: Prosci

Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.

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Anti-PTK2 Rabbit Polyclonal Antibody

Catalog Number: (10814-148)

Supplier: Prosci

Description: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

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Anti-IGF1R Rabbit Polyclonal Antibody

Catalog Number: (89276-688)

Supplier: Genetex

Description: Rabbit polyclonal antibody to IGF-1R (phospho Y1161)

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Anti-ABL1 Rabbit Polyclonal Antibody

Catalog Number: (89276-902)

Supplier: Genetex

Description: Rabbit polyclonal antibody to Abl1 (phospho Y204)

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Anti-KDR Rabbit Polyclonal Antibody

Catalog Number: (89304-160)

Supplier: Genetex

Description: Rabbit polyclonal antibody to VEGFR-2 (phospho Tyr1214)

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Anti-SYK Rabbit Polyclonal Antibody

Catalog Number: (10814-076)

Supplier: Prosci

Description: Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion

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Anti-DOK2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10351-308)

Supplier: Bioss

Description: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]