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Image Unavailable-TCM1759-1G

Methyl (phenyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosid)uronate ≥98.0% (by HPLC)

Description: CAS Number: 62812-42-4
Molecular Formula: C19H22O9S
Molecular Weight: 426.44
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 119
Specific rotation [a]20/D: -19 deg (C=1, CHCl3)
Storage Temperature: 0-10°C
Catalog Number: TCM1759-1G
Supplier: TCI America

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Product Image-CAPI17850

Pierce™ Agarose I (Molecular Biology Grade), Thermo Scientific

Description: Thermo Scientific Pierce Agaroses are highly purified and carefully blended formulations of regular that provide uniform lot-to-lot consistency for preparation of electrophoresis gels.
Catalog Number: CAPI17850
Supplier: Thermo Scientific

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Image Unavailable-CAPIPA5-12888

Anti-PDPK1 Rabbit Polyclonal Antibody

Description: PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis. Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.
Catalog Number: CAPIPA5-12888
Supplier: Thermo Scientific
Image Unavailable-77437-014

Anti-PTEN Rabbit Polyclonal Antibody

Description: Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN/MMAC1 discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism.
Catalog Number: 77437-014
Supplier: Bioss
Image Unavailable-103011-314

Resorufin-β-D-galactopyranoside

Description: Unlike FDG that requires a two-step hydrolysis to generate maximum fluorescence, resorufin β-D-galactopyranoside requires only a single-step hydrolysis reaction to attain full fluorescence. This substrate is especially useful for sensitive enzyme measurements in ELISAs. The relatively low pKa (~6.0) of resorufin (the enzymatic hydrolysis product of resorufin galactoside) with Ex/Em=573/585 nm permits continuous measurement of enzymatic activity. Resorufin galactoside has also been used to quantitate β-galactosidase activity in single yeast cells by flow cytometry and to detect immobilized β-galactosidase activity.
Catalog Number: 103011-314
Supplier: Anaspec Inc
Image Unavailable-TCP1666-25G

Pyridine hydrobromide ≥98.0% (by HPLC, titration analysis)

Description: CAS Number: 18820-82-1
MDL Number: MFCD00012801
Molecular Formula: C5H5N
Molecular Weight: 160.01
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Melting point (°C): 217
Catalog Number: TCP1666-25G
Supplier: TCI America

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Image Unavailable-CAAAAL15407-06

2-Bromo-4'-(1-pyrrolidinyl)acetophenone 97%

Description: 2-Bromo-4'-(1-pyrrolidinyl)acetophenone 97%
Catalog Number: CAAAAL15407-06
Supplier: Thermo Scientific Chemicals
Image Unavailable-10417-340

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy7®)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: 10417-340
Supplier: Bioss
Image Unavailable-TCB3256-5G

9-Bromo-1-nonene ≥95.0% (by GC)

Description: 9-Bromo-1-nonene, Purity: >95.0%(GC), CAS Number: 89359-54-6, Molecular Formula: C9H17Br, Molecular Weight: 205.14, Synonyms: 8-Nonenyl Bromide, Color: Colorless - Almost colorless, Size: 1G
Catalog Number: TCB3256-5G
Supplier: TCI America
Image Unavailable-CAAAA15288-14

(4-Nitrobenzyl)triphenylphosphonium chloride 98%

Description: (4-Nitrobenzyl)triphenylphosphonium chloride 98%
Catalog Number: CAAAA15288-14
Supplier: Thermo Scientific Chemicals

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Product Image-89158-218

PPP ≥98% (by HPLC)

Description: A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenografted and allografted mice. Picropodophyllin downregulates IGF-1R by interfering with the action of β-arrestin 1/MDM2. It causes tumor regression and attenuates invasiveness of uveal melanoma cells. It displays beneficial effects on tumor growth, angiogenesis, bone disease and survival in a mouse multiple myeloma model. It attenuates intimal hyperplasia after vascular injury. Inhibition of IGF-1R is non-competitive with ATP.
Catalog Number: 89158-218
Supplier: Enzo Life Sciences
Image Unavailable-76082-728

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: 76082-728
Supplier: Bioss
Product Image-10073-194

Anti-BTK Mouse Monoclonal Antibody [clone: 7F12H4]

Description: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases.All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini.BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation.
Catalog Number: 10073-194
Supplier: Prosci
Product Image-470232-864

Wallcur® PRACTI-Powders

Description: For Reconstitution Practice!
Catalog Number: 470232-864
Supplier: WALLCUR, LLC.
Product Image-76262-946

Anti-PIK3CB Rabbit Polyclonal Antibody

Description: PIK3CB is a catalytic subunit of phosphoinositide-3-kinase beta. PIK3CB catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration and cell survival. PTEN reverses this process. PI3K signaling pathway is constitutively activated in human cancers that have loss of function of PTEN. Furthermore, PI3KCB down regulation can suppress cell growth in malignant gliomas. Anti-PIK3C beta Antibody is suitable for researcher in Cancer, Immunology and Nuclear Signaling research.
Catalog Number: 76262-946
Supplier: Rockland Immunochemical
Image Unavailable-CAAAAL09553-03

α,2-Dibromo-5-fluorotoluene 97%

Description: α,2-Dibromo-5-fluorotoluene 97%
Catalog Number: CAAAAL09553-03
Supplier: Thermo Scientific Chemicals

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