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Description: This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), LK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011].
Catalog Number: 10231-128
Supplier: Bioss


Description: Excellent for temporary storage or display.
Catalog Number: 470022-330
Supplier: CHARLES W. KANTY


Description: Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9); involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.
Catalog Number: 10434-520
Supplier: Bioss


Description: For excipient use only. Can be used for production of dialysis solutions.
Catalog Number: 89234-906
Supplier: Macco Organiques S.R.O

Description: Convenient triple memories recall minimum/maximum readouts for relative humidity, dew point, and temperature.
Catalog Number: 89500-398
Supplier: VWR International

Description: Hi/Lo Alarms and Time/Date Stamps: Unique alarm settings can be programmed for both humidity and temperature parameters
Catalog Number: 76047-582
Supplier: VWR International


Description: Pocket pen is ideal for measuring humidity and temperature quickly and easily.
Catalog Number: 35519-049
Supplier: VWR International


Description: Displays current, minimum, and maximum values for dew point, wet-bulb, humidity, and temperature.
Catalog Number: 36934-164
Supplier: VWR International

Description: Units take measurements across a wide humidity range and simultaneously display humidity and temperature.
Catalog Number: 33500-098
Supplier: VWR International

Description: Provides a permanent record by printing current humidity, temperature, dew point, time, and date.
Catalog Number: 23609-226
Supplier: VWR International

UL Listed CSA Certified


Description: Traceable® Memory-Card Humidity/Temperature/Dew Point meter is a stand-alone unit with data logging capabilities.
Catalog Number: 89369-158
Supplier: VWR International

Description: These crucibles are great for student use.
Catalog Number: 470006-204
Supplier: Wards


Description: A variety of colorful collections to introduce rocks, minerals and fossils.
Catalog Number: 470025-268
Supplier: TREASURE CREEK MINERALS, LLC.


Description: Hi/Lo Alarms and Time/Date Stamps: Unique alarm settings can be programmed for both humidity and temperature parameters
Catalog Number: 76047-586
Supplier: VWR International


Description: Digital hygrometers are ideal for critical experiments, routine measurements, and continuous monitoring applications, and are suitable for all quality control needs.
Catalog Number: 35519-046
Supplier: VWR International

Description: Rugged, handheld, portable unit is ideal for monitoring conditions for chambers, cleanrooms, food processing, labs, and all humidity-sensitive manufacturing operations.
Catalog Number: 61161-380
Supplier: VWR International