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Description: Diethyl trans-1,2-Cyclopropanedicarboxylate, Purity: >96.0%(GC), CAS Number: 3999-55-1, MF: C9H14O, MW: 186.21, Synonym: trans-1,2-Cyclopropanedicarboxylic Acid Diethyl Ester, Form: Clear, Liquid, Color: Colorless - Very pale yellow, Size: 1G
Catalog Number: TCD4743-5G
Supplier: TCI America

Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Catalog Number: 10070-446
Supplier: Prosci


Description: trans-5-Decen-1-ol 96%
Catalog Number: CAAAAL11768-03
Supplier: Thermo Scientific Chemicals

Description: 4-(trans-4-Propylcyclohexyl)cyclohexanone, Purity: >98.0%(GC), CAS Number: 82832-73-3, Molecular Formula: C15H26O, Molecular Weight: 222.37, Size: 1G
Catalog Number: TCP2108-5G
Supplier: TCI America


Description: CAS Number: 14755-02-3
MDL Number: MFCD00004390
Molecular Formula: C9H8O3
Molecular Weight: 164.16
Purity/Analysis Method: >99.0% (GC,T)
Form: Crystal
Melting point (°C): 196
Catalog Number: TCC0655-025G
Supplier: TCI America


Description: trans-Cinnamic acid 99+%
Catalog Number: CAAAA13538-36
Supplier: Thermo Scientific Chemicals

Description: trans-2-Nonenal 97%
Catalog Number: CAAAA18108-06
Supplier: Thermo Scientific Chemicals

Description: trans-2-Hexenyl acetate 98%
Catalog Number: CAAAA18786-18
Supplier: Thermo Scientific Chemicals

Description: CAS Number: 1011-54-7
MDL Number: MFCD00064238
Molecular Formula: C10H10O3
Molecular Weight: 178.19
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 186
Catalog Number: TCM0449-025G
Supplier: TCI America

Description: trans-4-Methylcyclohexanol 98%
Catalog Number: CAAAB20054-14
Supplier: Thermo Scientific Chemicals

Description: Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
Catalog Number: 10371-904
Supplier: Bioss


Description: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Catalog Number: 10467-452
Supplier: Bioss


Description: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Catalog Number: 10467-454
Supplier: Bioss


Description: NOL1, (synonyms: p120, NSUN1, NOP120), is a 120 kDa proliferating-cell nucleolar antigen and is the most cancer specific of the proliferation-associated nucleolar proteins identified thus far. NOL1 is expressed in G1 and peaks during the early S phase of the cell cycle and it has not been detected in benign tumors and most normal resting tissues. Overexpression of NOL1 caused the transformation of NIH 3T3 cells and expression of an antisense NOL1 construct inhibited the growth of NIH 3T3 cells. NOL is localized in a novel nucleolar microfibrillar structure, and contains, consecutively, four major domains: a basic domain, an acidic domain, a hydrophobic and methionine-rich domain, and a domain rich in cysteine and proline residues. The gene for human NOL1 was assigned to chromosome 12p13.
Catalog Number: 10091-210
Supplier: Proteintech


Description: Trans,trans-4'-Ethyl-4-(3,4,5-trifluorophenyl)bicyclohexyl, Purity: >98%(GC), CAS: 139215-80-8, Molecular Formula: C20H27F3, Molecular Weight: 324.43, Physical state: Solid, Form: Crystal- Powder, Colour: White - Almost white, Size: 25G
Catalog Number: TCE1156-5G
Supplier: TCI America

SDS


Description: trans,trans-Muconic acid (trans,trans-1,3-butadiene-1,4-dicarboxylic acid) 98+%
Catalog Number: CAAAAL03987-06
Supplier: Thermo Scientific Chemicals