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Water, Assurance® Grade Blank for ICP, for atomic absorption spectroscopy, deionized

Supplier: SPEX CERTIPREP LLC
Description: Calibration and Matrix Blanks

Certificates

Product Image-10748-248

Anti-CFLAR Rabbit Polyclonal Antibody

Catalog Number: (10748-248)
Supplier: Prosci
Description: FLIP Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP3-7. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors. Four splice variants of c-FLIPs have been identified and termed FLIPalpha, beta, gamma, and delta, respectively.
Image Unavailable-H-4982.1000BA

Pig Galanin-Like Peptide Trifluoroacetate

Supplier: Bachem Americas
Description: This member of the galanin family has been isolated from porcine hypothalamus. It is a 60 amino acid peptide that, unlike galanin, has a non-amidated C-terminus. GALP amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) portion of galanin. Receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2; IC₅₀ = 0.24 nM) and a lower affinity for the GALR1 receptor (IC₅₀ = 4.3 nM). GALP is therefore an endogenous ligand that preferentially binds the GALR2 receptor, whereas galanin is relatively non-selective.

Product Image-10748-222

Anti-CASP10 Rabbit Polyclonal Antibody

Catalog Number: (10748-222)
Supplier: Prosci
Description: Caspase-10 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch4 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which causes the proteolytic cleavage of many key proteins such as PARP. Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death. Caspase-10 is expressed in many tissues and cell lines.
Product Image-89415-288

Anti-FLIP Rabbit Polyclonal Antibody

Catalog Number: (89415-288)
Supplier: Prosci
Description: FLIP Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and c-FLIPs, respectively. The human FLIPs were also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH, CLARP and usurpin. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors CD95, DR3, TRAIL-R and TNFR1. Four splice variants of c-FLIPs have been identified and termed FLIPalpha, beta, gamma, and delta, respectively.
Product Image-RC5307.2-4

Nitrate Standard, 1 ml = 0.200 mg NO₃, 200 ppm NO₃⁻, Ricca Chemical Company

Catalog Number: (RC5307.2-4)
Supplier: Ricca Chemical
Description: 200 ppm NO3 (NaNO3 in water). For ion chromatography. Clear, colorless. NIST traceable. 120mL.

SDS Certificates Small Business Enterprise


Product Image-VWRL0201-1000

Water, Molecular Biology Grade

Supplier: VWR
Description: VWR® Molecular Biology Grade Water is 0.2 um filtered, free of DEPC (Diethyl pyrocarbonate) and other chemical additives. The product is extremely low in endotoxin and has been analyzed for the absence of DNase, RNase and Protease. It is suitable in molecular biology research applications.

SDS Certificates Product available on GSA Advantage®

Product Image-55708-880

Accessories for CryoStorage Systems Taylor-Wharton, IC Biomedicals

Supplier: Taylor-Wharton
Description: Cryopreservation system, Cannister for Samples

Product Image-RC5307.1-16

Nitrate Standard, 1 ml = 0.100 mg NO₃⁻, 100 ppm NO₃⁻, Ricca Chemical Company

Catalog Number: (RC5307.1-16)
Supplier: Ricca Chemical
Description: 100 ppm NO3 (NaNO3 in water). For ion chromatography. Clear, colorless. NIST traceable. 500mL.

SDS Certificates Small Business Enterprise


Product Image-76285-238

Water USP for irrigation, sterile

Supplier: NURSE ASSIST, INC.
Description: Water USP for irrigation, sterile

Certificates

Image Unavailable-BJ69508-1L

Acetone ≥99.9%, TraceSELECT™ for inorganic trace analysis, Riedel-de Haën™

Catalog Number: (BJ69508-1L)
Supplier: Honeywell Research Chemicals
Description: High purity solvents for speciation analysis by LC-ICP-MS. Rigorous purification procedures followed by UV spectroscopy, IC, and ICP-MS testing to assure high chemical purity and high UV transmittance. The blank values for metal traces in these solvents are in the ppb range or lower.

SDS Certificates Environmentally Preferable


Image Unavailable-89155-992

Caspase Inhibitor Set

Catalog Number: (89155-992)
Supplier: Enzo Life Sciences
Description: Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, DEVD is the recognition sequence for caspase-3/CPP32, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/ FLICE, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.   
Product Image-RC3172-16

Fluoride Standard, 1 ml = 0.5 mg F-, 500 ppm F-, Ricca Chemical Company

Catalog Number: (RC3172-16)
Supplier: Ricca Chemical
Description: 500 ppm F (NaF in water). For ion chromatography. Clear, colorless, odorless. NIST traceable. 500mL.

SDS Certificates Small Business Enterprise


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WP9QY Trifluoroacetate

Catalog Number: (N-1685.0001BA)
Supplier: Bachem Americas
Description: The TNF-α antagonist WP9QY inhibited TNF-α mediated apoptosis and exhibited an IC₅₀ of 5 µM in the binding assay. YCWSQYLCY is the smallest peptidomimetic developed to date that might be used as a lead compound for the next generation of non-peptidic inhibitors. The name WP9QY arises from the binding to the site observed in the TNF-β/TNF-receptor(I) complex designated WP9 and the introduction of the amino acids Gln and Tyr.
Product Image-RC3171-8

Fluoride Standard, 1 ml = 0.1 mg F-, 100 ppm F-, Ricca Chemical Company

Supplier: Ricca Chemical
Description: 100 ppm =100 µg/mL

SDS Certificates Small Business Enterprise

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SP2509 ≥95%

Supplier: Adipogen
Description: LSD1 is a promising target for cancer therapy. Epigenetic control of histone methylation is frequently associated with oncogenesis and LSD1 is overexpressed in many types of cancer. siRNA knockdown of LSD1 has been shown to suppress growth of cancer cells. SP-2528 is a selective and reversible LSD1 inhibitor with an IC(50) of 10nM. SP-2528 demonstrates a high specificity for LSD1, with no effect on MAOi.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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