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Image Unavailable-10462-606

Anti-SLC25A28 Rabbit Polyclonal Antibody (Cy5®)

Description: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.
Catalog Number: 10462-606
Supplier: Bioss
Product Image-77522-890

Rat IREB2 (Iron Responsive Element Binding Protein 2) ELISA Kit

Description: Rat IREB2 (Iron Responsive Element Binding Protein 2) ELISA Kit
Catalog Number: 77522-890
Supplier: AFG Bioscience
Product Image-75836-098

Histology Control Slides, Iron (Ferric), Springside Scientific

Description: 100% Human Tissue.
Catalog Number: 75836-098
Supplier: SPRINGSIDE SCIENTIFIC, LLC.
Image Unavailable-76109-010

Anti-Hepcidin 25 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
Catalog Number: 76109-010
Supplier: Bioss
Image Unavailable-10664-312

Anti-MMS19 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Catalog Number: 10664-312
Supplier: Bioss
Image Unavailable-10664-308

Anti-MMS19 Rabbit Polyclonal Antibody (Cy3®)

Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Catalog Number: 10664-308
Supplier: Bioss
Product Image-10104-168

Anti-FTH1 Rabbit Polyclonal Antibody

Description: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number: 10104-168
Supplier: Prosci
Image Unavailable-10664-986

Anti-HAMP Rabbit Polyclonal Antibody

Description: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
Catalog Number: 10664-986
Supplier: Bioss
Product Image-470163-030

Bursting Bottle

Description: A fascinating demonstration!
Catalog Number: 470163-030
Supplier: Wards
Product Image-10099-798

Anti-SLC25A28 Rabbit Polyclonal Antibody

Description: SLC25A28 is a mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe (2+), is then probably delivered to ferrochelatase to catalyze Fe (2+) incorporation into protoprophyrin IX to make heme.
Catalog Number: 10099-798
Supplier: Prosci
Image Unavailable-TCB0915-005G

1,1'-Dibenzoylferrocene ≥98.0%

Description: CAS Number: 12180-80-2
MDL Number: MFCD00045455
Molecular Formula: C24H18FeO2
Molecular Weight: 394.25
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 103
Catalog Number: TCB0915-005G
Supplier: TCI America

SDS


Image Unavailable-76109-546

Anti-MMS19 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Catalog Number: 76109-546
Supplier: Bioss
Product Image-470005-394

Gilley Induction Coil Set

Description: An excellent set of materials for demonstrating electromagnetism and induced currents, the set includes two electromagnetic coils mounted on plastic saddle blocks, round and square iron cores, split round iron cores, a double core, and a card for showing lines of force. Set of two.
Catalog Number: 470005-394
Supplier: Wards
Product Image-470101-476

A-Frame Base with Rod

Description: These cast-iron bases have three-point stability on nearly any surface.
Catalog Number: 470101-476
Supplier: Wards
Product Image-470165-370

A-Shaped Base Retort Stand

Description: This cast iron, powder-coated, A-shaped base includes a stainless steel rod.
Catalog Number: 470165-370
Supplier: Wards
Image Unavailable-75791-062

Human Recombinant Hepcidin (from E. coli)

Description: Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.
Catalog Number: 75791-062
Supplier: Prosci
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