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Image Unavailable-10366-994

Anti-GRIN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Catalog Number: 10366-994
Supplier: Bioss
Image Unavailable-10366-992

Anti-GRIN1 Rabbit Polyclonal Antibody (Cy7®)

Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Catalog Number: 10366-992
Supplier: Bioss
Image Unavailable-76100-936

Anti-GLUR4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.
Catalog Number: 76100-936
Supplier: Bioss
Product Image-10101-944

Anti-GRIK5 Rabbit Polyclonal Antibody

Description: GRIK5 is a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. GRIK5 forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number: 10101-944
Supplier: Prosci
Image Unavailable-76100-942

Anti-Group I mGLUR Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions.
Catalog Number: 76100-942
Supplier: Bioss
Image Unavailable-TCT3105-25G

DL-Threonine ≥97.0% (by titrimetric analysis) (contains DL-Allothreonine)

Description: DL-Threonine (contains DL-Allothreonine), Purity/Analysis Method: >97.0%(T), CAS Number: 80-68-2, Molecular formula: C4H9NO3, Molecular weight: 119.12, Size: 100G
Catalog Number: TCT3105-25G
Supplier: TCI America
Image Unavailable-89361-954

Anti-GS Goat Polyclonal Antibody

Description: Glutamine Synthetase (GS) catalyzes the conversion of ammonia and glutamate to glutamine. This reaction consumes a molecule of ATP:Glutamate + NH4+ + ATP --> Glutamine + ADP + Pi. GS is found in astrocytes as an octamer of identical 45kDa subunits. The function of GS is the detoxification of brain ammonia. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. On the other hands, the level of expression of GS is increased during ischemia in vivo or hypoxia in culture.
Catalog Number: 89361-954
Supplier: Genetex
Image Unavailable-CA61000-136

Mineral Modified Glutamate Medium Base, HiMedia Laboratories

Description: Base medium is used for enumeration of coliform bacteria in water and waste water.
Catalog Number: CA61000-136
Supplier: HiMedia

SDS Certificates


Image Unavailable-89349-860

Anti-MGLUR5 Rabbit Polyclonal Antibody

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors (GPCRs) that contain 7 membrane-spanning domains and a large extracellular N-terminal region. The group I receptors mGluR1 and mGluR5 activate phospholipase C. By screening a human brain cDNA library with a rat mGluR1-alpha cDNA under low stringency conditions, Minakami et al. (1993) and Minakami et al. (1994) isolated human cDNAs encoding mGluR5. Minakami et al. (1993) identified a longer isoform of mGluR5 (mGluR5B).
Catalog Number: 89349-860
Supplier: Genetex
Product Image-89358-478

Anti-ATE1 Rabbit Polyclonal Antibody

Description: This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]
Catalog Number: 89358-478
Supplier: Genetex
Product Image-10372-190

Anti-GRIN1 Rabbit Polyclonal Antibody

Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Catalog Number: 10372-190
Supplier: Bioss
Image Unavailable-CAAAJ62777-MD

Ivermectin

Description: Antiparasitic and macrolide antibiotic. Modulates glutamate-GABA-activated chloride channels. Also activates the glycine receptor chloride channel
Catalog Number: CAAAJ62777-MD
Supplier: Thermo Scientific Chemicals

Certificates


Product Image-10101-152

Anti-GRIK2 Rabbit Polyclonal Antibody

Description: GRIK2 encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus.
Catalog Number: 10101-152
Supplier: Prosci
Image Unavailable-10414-026

Anti-GRIA2 Rabbit Polyclonal Antibody (Cy7®)

Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Catalog Number: 10414-026
Supplier: Bioss
Product Image-10101-154

Anti-GRIK2 Rabbit Polyclonal Antibody

Description: This gene, GRIK2, encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.
Catalog Number: 10101-154
Supplier: Prosci
Image Unavailable-76101-186

Anti-Metabotropic Glutamate Receptor 4+6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Catalog Number: 76101-186
Supplier: Bioss
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