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Product Image-10075-720

Anti-GRIA2 Rabbit Polyclonal Antibody

Catalog Number: (10075-720)
Supplier: Prosci
Description: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003; Seidenman et al., 2003; Chung et al., 2003; Yan et al., 2002).
Product Image-10106-584

Anti-TFAM Rabbit Polyclonal Antibody

Catalog Number: (10106-584)
Supplier: Prosci
Description: TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Image Unavailable-10482-288

Anti-PANK4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10482-288)
Supplier: Bioss
Description: PANK4 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the physiological regulation of the intracellular coenzyme A (CoA) concentration. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.
Image Unavailable-89360-862

Anti-PTP1C Mouse Monoclonal Antibody [clone: PTY10]

Catalog Number: (89360-862)
Supplier: Genetex
Description: Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.
Image Unavailable-10450-724

Anti-TLR7 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10450-724)
Supplier: Bioss
Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Image Unavailable-10665-800

Anti-SPTLC2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10665-800)
Supplier: Bioss
Description: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
Product Image-10782-010

Anti-POMC Guinea Pig Polyclonal Antibody

Catalog Number: (10782-010)
Supplier: Biosensis
Description: Proopiomelanocortin (POMC) is the precursor of the melanocortin peptides alpha, beta and gamma. POMC neurons in the arcuate nucleus of the hypothalamus function as key central regulators of food intake and homeostatic control of energy balance in both rodents and non-human primates. MSH increases the pigmentation of skin by increasing the melanin production in melanocytes. MSH is produced in the pituitary gland and belongs to the POMC family.
Image Unavailable-10450-728

Anti-TLR7 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10450-728)
Supplier: Bioss
Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Image Unavailable-10665-794

Anti-SPTLC2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10665-794)
Supplier: Bioss
Description: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
Image Unavailable-10665-792

Anti-SPTLC2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10665-792)
Supplier: Bioss
Description: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
Product Image-10085-792

Anti-DGKB Rabbit Polyclonal Antibody

Catalog Number: (10085-792)
Supplier: Proteintech
Description: DGKB(Diacylglycerol kinase beta) is also named as DAGK2, KIAA0718 , 90 kDa diacylglycerol kinase and belongs to the eukaryotic diacetylglycerol kinase family. It is a key enzyme in lipid metabolism that functions to reintroduce diacylglycerol formed from the hydrolysis of phospholipids into the biosynthetic pathway. This protein has 2 isoforms produced by alternative splicing with the molecular weight of 87 kDa and 91 kDa.
Image Unavailable-CAPIPA5-18293

Anti-LNK/SH2B3 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18293)
Supplier: Thermo Scientific
Description: This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
Image Unavailable-10450-730

Anti-TLR7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10450-730)
Supplier: Bioss
Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Image Unavailable-10665-790

Anti-SPTLC2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10665-790)
Supplier: Bioss
Description: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
Product Image-10097-276

Anti-ZFYVE27 Rabbit Polyclonal Antibody

Catalog Number: (10097-276)
Supplier: Proteintech
Description: ZFYVE27, also named as Protrudin, is a 411 amino acid protein, which contains 1 FYVE-type zinc finger. ZFYVE27 localizes in the recycling endosome membrane and functions as an upstream inhibitor of RAB11, regulating directional protein transport to the forming neurites. ZFYVE27 is a key regulator of vesicular transport during neurite extension and is involved in neuronal intracellular trafficking in the corticospinal tract.
Image Unavailable-10450-714

Anti-TLR7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (10450-714)
Supplier: Bioss
Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
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