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Image Unavailable-CAPIPA5-15577

Anti-PPP2R1A Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-15577)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, porcine and rabbit based on sequence homology. PPP2CA/B represents the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
Image Unavailable-76108-966

Anti-CTDSPL Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76108-966)
Supplier: Bioss
Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Image Unavailable-10332-710

Anti-CDK10 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10332-710)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Image Unavailable-CAPIPA5-14050

Anti-MAPK11 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-14050)
Supplier: Thermo Scientific
Description: MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
Image Unavailable-10391-442

Anti-PRKAA1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10391-442)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
Image Unavailable-10391-426

Anti-PRKAA1 Rabbit Polyclonal Antibody

Catalog Number: (10391-426)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
Image Unavailable-76116-502

Anti-DAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76116-502)
Supplier: Bioss
Description: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
Image Unavailable-10081-196

Anti-PRKACB Rabbit Polyclonal Antibody

Catalog Number: (10081-196)
Supplier: Proteintech
Description: PRKACB, also named as PKA C-beta, belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family and cAMP subfamily. It mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
Image Unavailable-10446-738

Anti-PP2A alpha + beta Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10446-738)
Supplier: Bioss
Description: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].
Image Unavailable-76077-652

Anti-ERK4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76077-652)
Supplier: Bioss
Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
Image Unavailable-10414-492

Anti-GRIN2B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10414-492)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Image Unavailable-10414-494

Anti-GRIN2B Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10414-494)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Product Image-BDH1160-4LP

Ethanol denatured (denatured with 5% isopropanol and 5% methanol), VWR Chemicals BDH®

Catalog Number: (BDH1160-4LP)
Supplier: VWR International
Description: Clear, colorless liquid. Denatured with 3.8–4.5% methanol and 4.0–5.0% 2-propanol. Suitable for cytology and histology.

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Image Unavailable-89361-012

Anti-PPP2R5B Goat Polyclonal Antibody

Catalog Number: (89361-012)
Supplier: Genetex
Description: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq]
Image Unavailable-10454-950

Anti-DAD1 Rabbit Polyclonal Antibody

Catalog Number: (10454-950)
Supplier: Bioss
Description: Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
Image Unavailable-76117-260

Anti-PP2A alpha/beta Tyr307 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76117-260)
Supplier: Bioss
Description: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
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