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Catalog Number: (10166-844)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to S100A9 (S100 calcium binding protein A9)


Catalog Number: (89279-438)
Supplier: Genetex
Description: Mouse Monoclonal antibody [S55-10] to Cav3.2


Catalog Number: (10424-428)
Supplier: Bioss
Description: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.


Catalog Number: (10401-590)
Supplier: Bioss
Description: Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP >ATP-gamma-S >2-methylthio-ATP = ADP.


Catalog Number: (10424-204)
Supplier: Bioss
Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.


Catalog Number: (10813-866)
Supplier: Prosci
Description: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2).


Supplier: Bachem Americas
Description: The somatostatin antagonist BIM 23627 selectively bound with high affinity to the human somatostatin receptor subtype 2 (hsst2), but was completely inactive in stimulating intracellular calcium mobilization. The IC₅₀ values of BIM 23627 to the five human somatostatin receptor subtypes were 2757 nM (hsst1), 6.4 nM (hsst2), 44 nM (hsst3), 423 nM (hsst4), and 86.5 nM (hsst5).

Catalog Number: (10369-044)
Supplier: Bioss
Description: Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk; Spleen tyrosine kinase; Tyrosine protein kinase SYK.


Catalog Number: (10401-612)
Supplier: Bioss
Description: Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP >ATP-gamma-S >2-methylthio-ATP = ADP.


Catalog Number: (76085-358)
Supplier: Bioss
Description: Membrane-bound, calcium-inhibitable adenylyl cyclase.


Catalog Number: (10452-608)
Supplier: Bioss
Description: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.


Catalog Number: (10372-722)
Supplier: Bioss
Description: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.


Catalog Number: (CAAAJ62728-MCR)
Supplier: Thermo Scientific Chemicals
Description: A calcium indicator; derivative of Fura-2 used to load the chelator into cells

Catalog Number: (10081-986)
Supplier: Proteintech
Description: CAMK2B(Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAM2, CAMK2 and CAMKB, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. CAMK2B is a member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. It plays a distinct role in the induction of anergy in T lymphocytes, by differential regulation of IL10 and IL2 gene transcription suggesting MEF2A as a molecular target which can integrate different calcium signals. This protein has 8 isoforms produced by alternative splicing with the molecular weight between 50 kDa and 73 kDa.


Catalog Number: (75789-166)
Supplier: Prosci
Description: Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.


Catalog Number: (77437-238)
Supplier: Bioss
Description: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.


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