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Description: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Catalog Number: 10666-158
Supplier: Bioss


Description: CARF was first cloned as a novel binding partner of ARF from a yeast interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
Catalog Number: 10399-976
Supplier: Bioss


Description: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Catalog Number: 10666-082
Supplier: Bioss


Description: A vasodilator agent which inhibits vascular smooth muscle contraction by acting as an intracellular calcium antagonist
Catalog Number: CAAAJ60594-03
Supplier: Thermo Scientific Chemicals

Description: Receptor for the CCL2, CCL7 and CCL12 chemokines. Transduces a signal by increasing intracellular calcium ion levels.
Catalog Number: 77439-802
Supplier: Bioss


Description: Rabbit Polyclonal antibody to Cav beta 2
Catalog Number: 89270-702
Supplier: Genetex


Description: Rabbit Polyclonal antibody to Cav1.1
Catalog Number: 89349-794
Supplier: Genetex


Description: Cyclohexanediamine tetraacetic acid standard solution. For Calcium and Total Hardness determination by Digital Titrator titration.
Catalog Number: CA11016-986
Supplier: Hach


Description: CACNB4 is a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Catalog Number: 10101-046
Supplier: Prosci


Description: Rabbit polyclonal antibody to S100Z
Catalog Number: 89290-148
Supplier: Genetex


Description: CASR, also named as GPRC2A, PCAR1, belongs to the G-protein coupled receptor 3 family. Changes in extracellular calcium are thought to modulate a balance between proliferation and differentiation in a variety of cell types. The activity of CASR is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. It has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. In normal primary keratinocytes and breast epithelial cells, proliferation is inhibited and elevated extracellular calcium levels trigger differentiation. Malignant transformations of these cell types are accompanied by a loss of responsiveness to the anti-proliferative effects of elevated extracellular calcium. Several disorders of calcium homeostasis have been linked to mutations in the CaSR. These include familial hypocalciuric hypercalcemia (FHH), neonatal severe hyperparathyroidism (NSHPT), and autosomal dominant hypocalemia (ADHypo).
Catalog Number: 10083-314
Supplier: Proteintech


Description: Rabbit polyclonal antibody to FAM26A (C-terminal)
Catalog Number: 89266-712
Supplier: Genetex


Description: Rabbit polyclonal to CaMKII alpha ( phospho T286 )
Catalog Number: 89361-704
Supplier: Genetex


Description: Rabbit polyclonal antibody to EFCAB3 (N-terminal)
Catalog Number: 89267-606
Supplier: Genetex


Description: This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
Catalog Number: 10078-282
Supplier: Prosci


Description: Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization.
Catalog Number: 77439-920
Supplier: Bioss


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