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Catalog Number: (10419-080)
Supplier: Bioss
Description: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].


Catalog Number: (76420-208)
Supplier: Corning


Catalog Number: (10390-130)
Supplier: Bioss
Description: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).


Catalog Number: (10390-116)
Supplier: Bioss
Description: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).


Catalog Number: (10372-714)
Supplier: Bioss
Description: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.


Catalog Number: (76107-204)
Supplier: Bioss
Description: This gene encodes a protein containing a coiled-coil domain. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. Localization of the orthologous rat protein suggests that it may play a role in neuronal injury response. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability.


Catalog Number: (76079-240)
Supplier: Bioss
Description: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.


Catalog Number: (89323-054)
Supplier: Genetex
Description: Phospholipase A2, group IVA (cytosolic, calcium-dependent) Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: IHC-P, WB Pkg Size: 100 ul


Catalog Number: (CA82021-512)
Supplier: G-Biosciences
Description: Molecular biology universal kit, contains 25 ml each of ammonium acetate, calcium chloride, EDTA, lithium acetate, magnesium chloride, potassium acetate, potassium chloride, SDS, sodium chloride, TE, Tris pH 7,0 and Tris pH 8,0


Catalog Number: (10209-534)
Supplier: Boster Biological Technology
Description: Rabbit IgG polyclonal antibody for Intermediate conductance calcium-activated potassium channel protein 4(KCNN4) detection. Tested with WB in Human;Mouse;Rat.


Catalog Number: (89271-198)
Supplier: Genetex
Description: Rabbit polyclonal antibody to ORAI3


Catalog Number: (CA10063-844)
Supplier: LONZA PHARMA - BIOSCIENCE CA
Description: A new robust and versatile serum-free medium formulation for high and low density NHEK-Normal Human Epidermal Keratinocyte cultures.


Catalog Number: (10341-576)
Supplier: Bioss
Description: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.


Catalog Number: (10491-066)
Supplier: Bioss
Description: Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1.


Catalog Number: (10751-138)
Supplier: Prosci
Description: SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.


Catalog Number: (76079-134)
Supplier: Bioss
Description: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.


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