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Image Unavailable-10332-742

Anti-EDNRB Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10332-742)
Supplier: Bioss
Description: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Image Unavailable-10332-740

Anti-EDNRB Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10332-740)
Supplier: Bioss
Description: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Image Unavailable-76101-708

Anti-CLDN11 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-708)
Supplier: Bioss
Description: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Product Image-10071-822

Anti-RPS6KB1 Rabbit Polyclonal Antibody

Catalog Number: (10071-822)
Supplier: Prosci
Description: RPS6KB1 phosphorylates the Ribosomal Protein-S6. Activation of RPS6KB1 requires a complex, ordered series of conformational changes and phosphorylation reactions. While the role of sequential, multi-site phosphorylation has been extensively detailed, characterization of the priming step required to initiate this cascade has remained elusive. Probably this priming process is dependent on calcium. Calcium-dependent regulation of RPS6KB1 does not specifically target Thr-229 and Thr-389, the key regulatory phosphorylation sites; rather, calcium chelation results in a global inhibition of RPS6KB1 phosphorylation. The initial calcium-dependent process is required to release an inhibitory interaction between the C- and N-termini of RPS6KB1, thus allowing phosphorylation of key domains. The priming event involves formation of a calcium-dependent protein complex that releases the interaction between the N- and C-termini. RPS6KB1 is then accessible for activation by the kinases that target the known regulatory phosphorylation sites.
Product Image-10103-292

Anti-ANO10 Rabbit Polyclonal Antibody

Catalog Number: (10103-292)
Supplier: Prosci
Description: TMEM16K is a multi-pass membrane protein. It belongs to the anoctamin family. TMEM16K may act as a calcium-activated chloride channel.
Product Image-10099-932

Anti-ATP2A3 Rabbit Polyclonal Antibody

Catalog Number: (10099-932)
Supplier: Prosci
Description: ATP2A3 is one of the SERCA Ca (2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.This gene encodes one of the SERCA Ca (2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
Image Unavailable-10339-120

Anti-EDNRB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10339-120)
Supplier: Bioss
Description: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Image Unavailable-10339-116

Anti-EDNRB Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10339-116)
Supplier: Bioss
Description: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Image Unavailable-76101-706

Anti-CLDN11 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76101-706)
Supplier: Bioss
Description: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Image Unavailable-CAPIPA5-18731

Anti-CACNA2D1 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18731)
Supplier: Thermo Scientific
Description: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Image Unavailable-75924-120

Anti-TMEM16A Mouse Monoclonal Antibody (CF594) [clone: DOG1.1]

Supplier: Biotium
Description: Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Image Unavailable-76109-006

Anti-IP3 Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76109-006)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Product Image-10338-476

Anti-CLDN11 Rabbit Polyclonal Antibody

Catalog Number: (10338-476)
Supplier: Bioss
Description: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Image Unavailable-10664-980

Anti-ITPR1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10664-980)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Image Unavailable-10664-976

Anti-ITPR1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10664-976)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Image Unavailable-10664-978

Anti-ITPR1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10664-978)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
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