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Catalog Number: (10671-568)
Supplier: Bioss
Description: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).


Catalog Number: (77438-554)
Supplier: Bioss
Description: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.


Catalog Number: (10477-126)
Supplier: Bioss
Description: This gene encodes a protein containing a coiled-coil domain. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. Localization of the orthologous rat protein suggests that it may play a role in neuronal injury response. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2011].


Catalog Number: (CA11008-276)
Supplier: Hach
Description: For sequential determination of Calcium and Total Hardness by EDTA Digital Titrator titration.

SDS


Catalog Number: (CAG8010-68015)
Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA
Description: Pre-optics cones and axial/radial windows for Agilent ICP-OES.


Catalog Number: (89356-822)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to PDE1A (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A)


Catalog Number: (10448-420)
Supplier: Bioss
Description: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.


Catalog Number: (77438-154)
Supplier: Bioss
Description: Intracellular calcium concentrations are regulated by a family of inositol phosphates, which act as second messengers in the calcium cell signaling pathway. ITPK1 (inositol 1,3,4-triphosphate 5/6 kinase), also known as ITRPK1, is a 414 amino acid monomer that belongs to the ITPK1 family and exists as two alternatively spliced isoforms. Widely expressed, ITPK1 is found at highest levels in brain, followed by heart, skeletal muscle, kidney, pancreas, liver, placenta and lung. ITPK1 contains one ATP-grasp domain and has been found to phosphorylate various.


Catalog Number: (10070-032)
Supplier: Prosci
Description: Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gammadependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion


Supplier: Thermo Scientific Chemicals
Description: Acts as a calcium chelator
Catalog Number: (89359-536)
Supplier: Genetex
Description: Receptor B for endothelin 1. Mediates its action by association with G proteins that activate a phosphatidylinositol calcium second messenger system.


Supplier: Biotium
Description: Fura-2, AM ester is a ratiometric fluorescent dye that binds to free intracellular calcium, and is the preferred dye for ratiometric imaging microscopy. Fura-2, AM ester is membrane-permeant and thus can be loaded into cells via incubation.

Catalog Number: (10390-116)
Supplier: Bioss
Description: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).


Catalog Number: (10390-130)
Supplier: Bioss
Description: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).


Supplier: Thermo Scientific Chemicals
Description: L-type calcium channel blocker
Catalog Number: (10751-138)
Supplier: Prosci
Description: SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.


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