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Image Unavailable-10390-106

Anti-ADCY8 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10390-106)
Supplier: Bioss
Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).
Product Image-10111-484

Anti-NUCB1 Rabbit Polyclonal Antibody

Catalog Number: (10111-484)
Supplier: Prosci
Description: Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of.-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis. Useful for immunohistochemistry and western blot.
Image Unavailable-76109-676

Anti-EFHA1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76109-676)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Image Unavailable-10390-114

Anti-ADCY8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10390-114)
Supplier: Bioss
Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).
Image Unavailable-76109-688

Anti-EFHD1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76109-688)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.
Image Unavailable-10450-798

Anti-MRGPRX1/3/4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10450-798)
Supplier: Bioss
Description: There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.
Image Unavailable-76078-724

Anti-Calreticulin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76078-724)
Supplier: Bioss
Description: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of Calcium homeostasis (By similarity).
Image Unavailable-75790-610

Human Recombinant Calcineurin Subunit B Type 1 (from E. coli)

Catalog Number: (75790-610)
Supplier: Prosci
Description: Calcineurin Subunit B Type 1 belongs to the calcineurin regulatory subunit family. Calcineurin Subunit B Type 1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase. It is composed of a catalytic subunit (A) and a regulatory subunit (B). It contains four EF-hand domains and four functional calcium-binding sites. Calcineurin Subunit B Type 1 plays an improtant role in the T cell activation pathway.
Image Unavailable-CAAAJ60076-18

Hydroxylapatite, fast flow

Supplier: Thermo Scientific Chemicals
Description: Used for fractionation and purification of proteins, enzymes, plasmids and nucleic acids.

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Image Unavailable-76079-238

Anti-Factor 7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76079-238)
Supplier: Bioss
Description: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Image Unavailable-10477-124

Anti-CCDC22 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10477-124)
Supplier: Bioss
Description: This gene encodes a protein containing a coiled-coil domain. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. Localization of the orthologous rat protein suggests that it may play a role in neuronal injury response. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2011].
Image Unavailable-10477-120

Anti-CCDC22 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10477-120)
Supplier: Bioss
Description: This gene encodes a protein containing a coiled-coil domain. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. Localization of the orthologous rat protein suggests that it may play a role in neuronal injury response. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2011].
Image Unavailable-89139-198

Fura 2-AM 1 mM in anhydrous DMSO fluorescent indicator, for calcium determination

Catalog Number: (89139-198)
Supplier: Biotium
Description: Fura-2, AM ester is a ratiometric fluorescent dye that binds to free intracellular calcium, and is the preferred dye for ratiometric imaging microscopy. Fura-2, AM ester is membrane-permeant and thus can be loaded into cells via incubation.
Product Image-10105-834

Anti-ASPH Rabbit Polyclonal Antibody

Catalog Number: (10105-834)
Supplier: Prosci
Description: ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.
Image Unavailable-75788-992

Human Recombinant Parvalbumin alpha (from E. coli)

Catalog Number: (75788-992)
Supplier: Prosci
Description: Parvalbumin alpha (PVALB) is a member of the parvalbumin family. PVALB is a high affinity calcium ion-binding protein, with two EF hand domains. PVALB is structurally and functionally similar to calmodulin and troponin C, it can bind two calcium ions. Parvalbumin is thought to be involved in relaxation after contraction in muscle. Parvalbumin is expressed in a specific population of GABAergic interneurons, which are believed to have a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus.
Image Unavailable-10426-418

Anti-CALR Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10426-418)
Supplier: Bioss
Description: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of Calcium homeostasis (By similarity).
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