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Catalog Number: (10455-876)
Supplier: Bioss
Description: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis.


Catalog Number: (10342-914)
Supplier: Bioss
Description: Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).


Catalog Number: (76085-126)
Supplier: Bioss
Description: Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.


Catalog Number: (76109-692)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Catalog Number: (10106-148)
Supplier: Prosci
Description: TRPM3 encodes a protein that belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The encoded protein mediates calcium entry, and this entry is potentiated by calcium store depletion.The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified.


Catalog Number: (77461-794)
Supplier: AAT BIOQUEST INC
Description: Rhod-4™ azide is an excellent building block that can be readily used to prepare a calcium-sensitive bioconjugate for monitoring calcium change spatially for a specific target.


Supplier: Abcam
Description: Anti-Calcium channel L type DHPR alpha 2 subunit/CACNA2D1 Rabbit Monoclonal Antibody [clone: EPR23267-59]

New Product

Supplier: Abcam
Description: Anti-Calcium channel L type DHPR alpha 2 subunit/CACNA2D1 Rabbit Monoclonal Antibody [clone: EPR23267-59]

New Product

Catalog Number: (ABCA_AB104416-100U)
Supplier: Abcam
Description: Anti-Calcium-independent Phospholipase A2/PLA2G6 Rabbit Polyclonal Antibody

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Catalog Number: (76085-116)
Supplier: Bioss
Description: Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.


Catalog Number: (10452-100)
Supplier: Bioss
Description: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.


Catalog Number: (89157-380)
Supplier: Enzo Life Sciences
Description: Major metabolite of vitamin D3. Mediates calcium and phosphorous homeostasis. Inhibits 1α,25-dihydroxyvitamin D3 and testosterone potentiation of calcium channels in osteosarcoma cells.


Catalog Number: (76739-362)
Supplier: ANTIBODIES.COM LLC
Description: Mouse Calcium-Independent Phospholipase A2/PLA2G6 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Calcium-Independent Phospholipase A2/PLA2G6 in serum, plasma, tissue homogenates, and other biological fluids.


Supplier: Abcam
Description: Anti-Sodium/calcium exchanger 2 Rabbit Monoclonal Antibody [clone: EPR25106-37]

New Product

Catalog Number: (CA11014-496)
Supplier: Hach
Description: Reagent set for the determination of Calcium Hardness by EDTA Digital Titrator Titration Method (Hach method 8204). Range: 100-4000 mg/L as CaCO3. Set contains CalVer® 2 Calcium Indicator Powder Pillows, Potassium Hydroxide Solution (8 N) and 0.800 M (EDTA) Digital Titrator Cartridge for approximately 40-100 tests.

SDS


Catalog Number: (CA11014-498)
Supplier: Hach
Description: Reagent set for the determination of Calcium Hardness by EDTA Digital Titrator Titration Method (Hach method 8204). Range: 10-160 mg/L as CaCO3. Set contains CalVer® 2 Calcium Indicator Powder Pillows, Potassium Hydroxide Solution (8 N) and 0.0800 M (EDTA) Digital Titrator Cartridge for approximately 40-100 tests.

SDS


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