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You Searched For: CL-82198+(MMP-13+inhibitor)


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Image Unavailable-76078-926

Anti-MMP-2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76078-926)
Supplier: Bioss
Description: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Image Unavailable-CAPIPA5-13199

Anti-MMP9 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13199)
Supplier: Thermo Scientific
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Image Unavailable-CA76634-500

Anti-TIMP-2 Mouse Monoclonal Antibody [clone: 3A4]

Catalog Number: (CA76634-500)
Supplier: Diagnostic Biosystems
Description: This antibody is specific to 21 kDa protein known as TIMP-2. TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMP are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2) and active form of 92 kDa type IV collagenase (MMP-9). TIMP inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Image Unavailable-102886-978

Anti-MMP7 Rat Monoclonal Antibody [clone: 704202]

Catalog Number: (102886-978)
Supplier: R&D Systems
Description: Mouse MMP-7 (Clone 704202), Host: Rat IgG2B, Monoclonal, Immunogen: Mouse myeloma cell line NS0-derived recombinant, Application: Intracellular Staining by Flow Cytometry
Image Unavailable-76078-928

Anti-MMP-2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76078-928)
Supplier: Bioss
Description: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Product Image-10080-156

Anti-MMP11 Rabbit Polyclonal Antibody

Catalog Number: (10080-156)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species Reactivity: Mouse, Rat, Isotype: IgG, Immunogen: Synthetic peptide from human MMP-11, Tested Applications: ELISA, IF, IHC, WB
Product Image-CA100-401-404

Anti-SPP1 Rabbit Polyclonal Antibody

Catalog Number: (CA100-401-404)
Supplier: Rockland Immunochemical
Description: Anti-Osteopontin is suitable for western blotting, immunochemistry (formalin-fixed paraffin-embedded sections) and ELISA. The antibody exclusively recognizes C-terminal fragments of both thrombin and MMP-cleaved OPN.
Image Unavailable-CA10816-810

Anti-MMP9 Mouse Monoclonal Antibody [clone: L51/82]

Catalog Number: (CA10816-810)
Supplier: Biolegend
Description: MMP-9 Monoclonal Antibody, Clone: L51/82, Host: Mouse, Isotype: IgG2a, Reactivity: Human, Mouse, Rat, Immunogen: against a full-length fusion protein corresponding to amino acids 1-708 of rat MMP9 protein, Conjugate: purified, Application: WB, IHC, Size: 100 ul
Product Image-10075-164

Anti-MMP23B Rabbit Polyclonal Antibody

Catalog Number: (10075-164)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit; Species Reactivity: Human; Immunogen: A synthetic peptide derived from C-Terminus of human MMP-23 protein; Isotype: IgG; Tested Applications: IHC, WB
Image Unavailable-10425-636

Anti-MMP23B Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10425-636)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Product Image-10662-274

MITO-ID® Membrane Potential Detection Kit, Enzo Life Sciences

Supplier: Enzo Life Sciences
Description: The Mito-ID® Membrane Potential Detection Kit has been optimized for measurement of mitochondria membrane potential (MMP) and cell viability by conventional fluorescence microscopy and flow cytometry.

Image Unavailable-102887-378

Anti-MMP17 Mouse Monoclonal Antibody [clone: 823511]

Catalog Number: (102887-378)
Supplier: R&D Systems
Description: Human MMP-17 monoclonal antibody (Clone 823511), Isotype: Mouse IgG2A, Immunogen: Mouse myeloma cell line NS0-derived, Applications: Neutralization, 500UG
Image Unavailable-CAPIPA5-13183

Anti-MMP14 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13183)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.
Product Image-10425-574

Anti-MMP23B Rabbit Polyclonal Antibody

Catalog Number: (10425-574)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Product Image-10075-178

Anti-MMP1 Rabbit Polyclonal Antibody

Catalog Number: (10075-178)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit; Species Reactivity: Human; Immunogen: A synthetic peptide from near C-Terminal of human MMP-1 protein; Isotype: IgG; Tested Applications: IHC, WB
Product Image-10080-476

Anti-MMP14 Rabbit Polyclonal Antibody

Catalog Number: (10080-476)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species reacivity: Human, Immunogen: A synthetic peptide derived from aa 160-173 of human MMP-14 protein, Tested application: IHC
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