You Searched For: CL-82198+(MMP-13+inhibitor)

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Human Recombinant MMP2 (from Cells)

Catalog Number: (75789-366)

Supplier: Prosci

Description: 72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. MMP-2 is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, atherosclerotic plaque rupture, as well as degrading extracellular matrix proteins. MMP-2 can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. MMP-2 cleaves KISS at a Gly-|-Leu bond and appears to have a role in myocardial cell death pathways.

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Mouse MMP-3 PicoKine ELISA Kit, Boster

Catalog Number: (10207-788)

Supplier: Boster Biological Technology

Description: Sandwich ELISA kit of Quantitative Detection for Mouse MMP-3

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Anti-MMP7 Rabbit Polyclonal Antibody

Catalog Number: (10109-554)

Supplier: Prosci

Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

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Matrix Metalloproteinase-14 (MMP-14) Colorimetric Drug Discovery Kit, Enzo Life Sciences

Catalog Number: (89156-482)

Supplier: Enzo Life Sciences

Description: A QuantiZymeTM Assay System

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Rat Matrix Metalloproteinase 10 (MMP-10) ELISA Kit

Catalog Number: (76703-936)

Supplier: AFG Bioscience

Description: Rat Matrix Metalloproteinase 10 (MMP-10) ELISA Kit

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Dog Matrix Metalloproteinase 3,MMP-3 ELISA Kit

Catalog Number: (76707-628)

Supplier: AFG Bioscience

Description: Dog Matrix Metalloproteinase 3,MMP-3 ELISA Kit

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Anti-RECK Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10348-134)

Supplier: Bioss

Description: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

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Anti-RECK Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76082-966)

Supplier: Bioss

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Anti-MMP1 Rabbit Polyclonal Antibody

Catalog Number: (10108-716)

Supplier: Prosci

Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.