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You Searched For: 2-Ethynylpyridine


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Anti-MSLN Rabbit Polyclonal Antibody

Description: Rabbit Polyclonal antibody to HERPUD1 (homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1)
Catalog Number: 89335-518
Supplier: Genetex
Product Image-12620-978

VWR® Dylatherm™ Hot Plate

Description: The economical Dylatherm™ hot plate features a large 16.5 cm (6<sup>1</sup>/<sub>2</sub>”) diameter cast aluminum top plate that provides an even heating surface capable of heating 1500 mL of water.
Catalog Number: 12620-978
Supplier: VWR International

Certificates UL Listed cUL Listed


Product Image-10153-320

VWR® Advanced Mini Dry Block Heater and Mini Dry Block Heater with Heated Lid, 230 V

Description: VWR® Advanced Mini Dry Block Heaters and Mini Dry Block Heaters with Heated Lid are ideal for a variety of applications that require accurate and repeatable results such as LAMP assays, immunoassays, enzyme reactions, and denaturations.
Catalog Number: 10153-320
Supplier: VWR International

Environmentally Preferable CE Compliant


Image Unavailable-H-6785.0500BA

Human GRP

Description: GRP, a bombesin-like peptide, is involved in stress-induced anorexia.
Catalog Number: H-6785.0500BA
Supplier: Bachem Americas
Product Image-89415-678

Anti-ARMER Rabbit Polyclonal Antibody

Description: ARMER Antibody: Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.
Catalog Number: 89415-678
Supplier: Prosci
Image Unavailable-10429-056

Anti-CPEB1 Rabbit Polyclonal Antibody

Description: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
Catalog Number: 10429-056
Supplier: Bioss
Image Unavailable-10436-018

Anti-CGRRF1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: CGR19 is involved in the negative regulation of cell proliferation and cell cycle arrest in response to stress.
Catalog Number: 10436-018
Supplier: Bioss
Image Unavailable-76119-188

Anti-GADD45 gamma Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Catalog Number: 76119-188
Supplier: Bioss
Product Image-10749-408

Anti-CASP12 Rabbit Polyclonal Antibody

Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
Catalog Number: 10749-408
Supplier: Prosci
Product Image-10749-562

Anti-CASP12 Rabbit Polyclonal Antibody

Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
Catalog Number: 10749-562
Supplier: Prosci
Product Image-89206-370

Orion™ Star™ A326 pH/Dissolved Oxygen Portable Multiparameter Meter, Thermo Scientific

Description: Accurately measure pH, dissolved oxygen and temperature with the Orion™ Star™ A326 pH/DO/RDO Portable Meter for high performance in challenging field tests.
Catalog Number: 89206-370
Supplier: Thermo Fisher Scientific
Image Unavailable-10084-730

Anti-CHOP Rabbit Polyclonal Antibody

Description: CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma. The observed molecular weight of CHOP is about 30 kDa.
Catalog Number: 10084-730
Supplier: Proteintech
Product Image-76221-262

Accessories for Oakton pH 150 Waterproof Portable Meter, Cole Parmer

Description: pH Meter, Oakton®, Oakton® RDO 450 replacement sensor cap
Catalog Number: 76221-262
Supplier: Antyila Scientific
Image Unavailable-10348-542

Anti-OXSR1 Rabbit Polyclonal Antibody

Description: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
Catalog Number: 10348-542
Supplier: Bioss
Image Unavailable-76083-030

Anti-OXSR1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
Catalog Number: 76083-030
Supplier: Bioss
Product Image-470353-778

Eisco® Fractures, Faults, and Dislocations Model

Description: <p>Geology model illustrating fault types and stress effects on rock layers for hands-on learning experiences.</p>
Catalog Number: 470353-778
Supplier: Wards
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