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Catalog Number: (10813-844)
Supplier: Prosci
Description: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.


Catalog Number: (10476-082)
Supplier: Bioss
Description: SRRM3


Catalog Number: (10068-914)
Supplier: Prosci
Description: Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.


Catalog Number: (10476-086)
Supplier: Bioss
Description: SRRM3


Catalog Number: (10476-080)
Supplier: Bioss
Description: SRRM3


Catalog Number: (89302-442)
Supplier: Genetex
Description: Rabbit polyclonal to SPINK5 (N-term)


Catalog Number: (10071-450)
Supplier: Prosci
Description: cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.


Catalog Number: (10070-036)
Supplier: Prosci
Description: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.


Catalog Number: (89141-420)
Supplier: Enzo Life Sciences
Description: Glycogen Synthase Kinase 3 (GSK3) exists in two isoforms, alpha and beta (GSK3α, and GSK3β). GSK3 is an active kinase that becomes phosphorylated by PKB/akt upon growth factor stimulation. Phosphorylation of GSK3α at serine 21 or GSK3β at serine 9, respectively, leads to inhibition of kinase activity of the GSK3.


Catalog Number: (10813-766)
Supplier: Prosci
Description: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).


Catalog Number: (89295-742)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to antithrombin III (FITC)


Catalog Number: (89289-332)
Supplier: Genetex
Description: Rabbit polyclonal antibody to STK39 (phospho Ser311)


Catalog Number: (10162-776)
Supplier: Genetex
Description: Rabbit polyclonal to LKB1 (phospho Ser428)


Catalog Number: (10068-922)
Supplier: Prosci
Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.


Catalog Number: (10495-116)
Supplier: Bioss
Description: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.


Catalog Number: (10813-968)
Supplier: Prosci
Description: In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.


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