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Product Image-10068-602

Anti-SPARC Rabbit Polyclonal Antibody

Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.
Catalog Number: 10068-602
Supplier: Prosci
Image Unavailable-CA89167-762

Taq DNA Polymerase, G-Biosciences

Description: G-Biosciences' recombinant Taq Polymerase is a highly thermostable DNA polymerase isolated from the thermophile, Thermus aquaticus
Catalog Number: CA89167-762
Supplier: G-Biosciences

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Product Image-10068-764

Anti-IRS1 Rabbit Polyclonal Antibody

Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
Catalog Number: 10068-764
Supplier: Prosci
Product Image-10068-676

Anti-PPARG Rabbit Polyclonal Antibody

Description: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.
Catalog Number: 10068-676
Supplier: Prosci
Product Image-10068-754

Anti-EGFR Rabbit Polyclonal Antibody

Description: Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
Catalog Number: 10068-754
Supplier: Prosci
Product Image-10070-926

Anti-MAPK3 Rabbit Polyclonal Antibody

Description: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1
Catalog Number: 10070-926
Supplier: Prosci
Image Unavailable-10407-042

Anti-AGPAT2 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Agpat2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. It is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Catalog Number: 10407-042
Supplier: Bioss
Product Image-10069-082

Anti-MME Rabbit Polyclonal Antibody

Description: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Catalog Number: 10069-082
Supplier: Prosci
Product Image-10070-882

Anti-FBXL4 Rabbit Polyclonal Antibody

Description: A member of the family of mammalian F-box proteins. F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 aminoacid motif, the F box (so named because cyclin F was one of the first proteins in which this motif was identified). Some F-box proteins have been shown to be critical for the controlled degradation of cellular regulatory proteins.
Catalog Number: 10070-882
Supplier: Prosci
Product Image-89138-878

Cheetah™ HotStart Taq DNA Polymerase, Biotium

Description: A hot-start Taq DNA polymerase modified using a novel modifying reagent, it has a faster activation time and better shelf-life.
Catalog Number: 89138-878
Supplier: Biotium
Product Image-10068-560

Anti-DOK2 Rabbit Polyclonal Antibody

Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
Catalog Number: 10068-560
Supplier: Prosci
Product Image-10071-464

Anti-KDR Rabbit Polyclonal Antibody

Description: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Catalog Number: 10071-464
Supplier: Prosci
Product Image-10069-048

Anti-TRPC6 Rabbit Polyclonal Antibody

Description: The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Catalog Number: 10069-048
Supplier: Prosci
Product Image-10075-504

Anti-PARK2 Rabbit Polyclonal Antibody

Description: Parkin is an E3 ligase in the ubiquitin-proteasome system. Hereditary Parkinson’s disease is most commonly caused by mutations in the parkin gene and is characterized by the progressive loss of dopaminergic neurons and the presence of Lewy bodies in the substania nigra (Jenner aet al.,1992). Recent evidence suggests that phosphorylation of parkin at Ser378 may have an important regulatory role on its E3 ubiquitin ligase activity (Yamamoto et al., 2005).
Catalog Number: 10075-504
Supplier: Prosci
Product Image-10068-998

Anti-ICAM1 Rabbit Polyclonal Antibody

Description: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Catalog Number: 10068-998
Supplier: Prosci
Product Image-10070-308

Anti-DOK1 Rabbit Polyclonal Antibody

Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Catalog Number: 10070-308
Supplier: Prosci
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