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Description: IL-10 is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. Inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFNγ), tumor necrosis factor alpha (TNFα), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. Suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Catalog Number: 77753-410
Supplier: VWR International

New Product


Description: IL-3 is a species-specific cytokine and pleiotropic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil, and mast cell lineages. Produced by T cells, mast cells, and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Catalog Number: 77753-360
Supplier: VWR International

New Product


Description: Sturdy, economical tools for handling, transferring, blending, or collecting chemical and biological samples.
Catalog Number: 82027-458
Supplier: VWR International

Description: IL-4 is an immunomodulatory cytokine that stimulates B cell proliferation and activates eosinophils, basophils, and mast cells. Induces vascular cell adhesion molecule (VCAM)-1 expression on endothelial cells and involved in collagen production by fibroblasts. Plays a key role in promotion of Th2 differentiation from naïve helper T cells. Defines the Th2 phenotype of lymphocytes. Regulates cell proliferation, apoptosis, and expression of numerous genes in various cell types. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Catalog Number: 77753-362
Supplier: VWR International

New Product


Description: IL-2C126S is an immunomodulatory cytokine that is produced by lymphocytes. IL-2C126S signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. Stimulates the proliferation and differentiation of B cells, natural killer (NK) cells, monocytes, and macrophages. Promotes proliferation and differentiation of CAR T cells, T cells, and NK cells. Activates and expands T cells and NK cells from peripheral blood. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Catalog Number: 77753-340
Supplier: VWR International

New Product


Description: These square weighing boats are flexible and feature smooth surfaces to provide accurate pour-outs with minimal sample loss.
Catalog Number: 76540-490
Supplier: VWR International

Description:

IL-7 promotes the stimulation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. IL-7, along with IL-2, 15, and 21, is a member of the common gamma (γc) chain cytokine family.
Secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes
Signals through its receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells
Is a regulator of intestinal mucosal lymphocyte proliferation
Promotes favorable phenotypes in adoptive cellular therapies such as CAR-T cell therapy when combined with IL-15. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

Catalog Number: 77753-374
Supplier: VWR International

New Product


Description: Look for the V at the neck.™ Economical, disposable tools for transferring, collecting, and handling chemical and biological materials.
Catalog Number: 80081-188
Supplier: VWR International

Description: Reference standard for measuring fluorescence quantum yield.
Catalog Number: 103010-740
Supplier: Anaspec Inc


Description: pH-dependent fluorescence; Maximum intensity observed in basic solutions.
Catalog Number: 103010-702
Supplier: Anaspec Inc


Description: Control standard endotoxin (CSE) is a widely used standard for endotoxin testing. It is a purified extract of <i>E. coli</i> O113:H10, the same strain used for the United States Pharmacopeia and the European Pharmacopeia reference standard endotoxin (RSE).
Catalog Number: MSPP-E01251
Supplier: ASSOCIATES OF CAPE COD INC MS


Description: Inactivated Helix Elite Molecular Standards are used for every step of the molecular testing process, from extraction, to amplification and detection.
Catalog Number: 10000-942
Supplier: MICROBIOLOGICS, INC.


Description: Comopatible with a variety of instruments, kits, and applications.
Catalog Number: 10753-290
Supplier: MICROBIOLOGICS, INC.

SDS


Description: The ZymoBIOMICS Microbial Community DNA Standard is designed to assess bias, errors and other artifacts after the step of nucleic acid purification.
Catalog Number: 77001-846
Supplier: Zymo Research


Description: Systems for vacuum filtration of aqueous solutions including cell culture media, buffers, or other biological fluids.
Catalog Number: 10040-446
Supplier: VWR International

Description: 2-AB labeled N-glycan standards and libraries provide high confidence in identification of samples. N-glycan (oligomannose 5) labeled with 2-aminobenzamide (2-AB).
Catalog Number: CAGKSB-103
Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA


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