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Image Unavailable-75841-672

Anti-CD3 Rat Monoclonal Antibody [clone: 17A2]

Catalog Number: (75841-672)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.
Image Unavailable-75841-498

Anti-CD11b (ICRF44) Mouse Monoclonal Antibody [clone: ICRF44]

Catalog Number: (75841-498)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.
Image Unavailable-75844-384

Anti-CD122 Rat Monoclonal Antibody [clone: TM-beta1]

Catalog Number: (75844-384)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TM-beta1 monoclonal antibody specifically reacts with mouse CD122, a beta chain shared by the IL-2 and IL-15 receptors. It is expressed by B cells, T cells, and NK cells and can be used as a marker for NK-cell progenitors. CD122 forms complexes involved in immunoregulation and signal transduction. The TM-beta1 antibody is reported to block the binding of IL-2 and IL-15 to the IL-2 beta receptor.
Image Unavailable-75844-456

Anti-IL-7Ra Rat Monoclonal Antibody (Biotin) [clone: A7R34]

Catalog Number: (75844-456)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.
Image Unavailable-75844-460

Anti-IL-7Ra Rat Monoclonal Antibody (Biotin) [clone: A7R34]

Catalog Number: (75844-460)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.
Image Unavailable-75843-114

Anti-CD69 Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: H1.2F3]

Catalog Number: (75843-114)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Image Unavailable-75843-170

Anti-CCR7 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 3D12]

Catalog Number: (75843-170)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.
We recommend that this antibody be incubated for at least 45 minutes at 4°C for optimal staining.
Image Unavailable-75843-464

Anti-IFNG Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: 4S.B3]

Catalog Number: (75843-464)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 4S.B3 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. The 4S.B3 antibody neutralizes IFN-γ.
Image Unavailable-75843-542

Anti-TER-119 Rat Monoclonal Antibody (BG Violet 450) [clone: TER-119]

Catalog Number: (75843-542)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells. 
Image Unavailable-75843-548

Anti-TER-119 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: TER-119]

Catalog Number: (75843-548)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells.
Image Unavailable-75843-536

Anti-TER-119 Rat Monoclonal Antibody (Biotin) [clone: TER-119]

Catalog Number: (75843-536)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells.
Image Unavailable-75842-878

Anti-CD51/CD61 Mouse Monoclonal Antibody [clone: 23C6]

Catalog Number: (75842-878)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.
Image Unavailable-75842-886

Anti-ITGB3 mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: VI-PL2]

Catalog Number: (75842-886)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
Image Unavailable-75841-662

Anti-CD3 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: Hit3a]

Catalog Number: (75841-662)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The Hit3a monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.
Image Unavailable-75843-080

Anti-CD8b Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: H35-17.2]

Catalog Number: (75843-080)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.
Image Unavailable-75843-078

Anti-CD8b Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: H35-17.2]

Catalog Number: (75843-078)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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