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Image Unavailable-75841-690

Anti-CD3 Mouse Monoclonal Antibody [clone: G4.18]

Catalog Number: (75841-690)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Image Unavailable-75842-016

Anti-CD27 Armenian Hamster Monoclonal Antibody [clone: LG.3A10]

Catalog Number: (75842-016)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.3A10 antibody is cross-reactive with human, mouse and rat CD27.
Image Unavailable-75842-378

Anti-TLR4 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: UT41]

Catalog Number: (75842-378)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The UT41 monoclonal antibody specifically reacts with mouse CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The UT41 antibody can bind to TLR4 with or without the formation of the TLR4/MD-2 complex.
Image Unavailable-75842-338

Anti-CSF1R Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: AFS98]

Catalog Number: (75842-338)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Image Unavailable-75842-300

Anti-CD154 Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: MR1]

Catalog Number: (75842-300)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Image Unavailable-75841-460

Anti-IL-2 (JES6-5H4) Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: JES6-5H4]

Catalog Number: (75841-460)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells. JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Image Unavailable-75841-464

Anti-IL-2 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: JES6-5H4]

Catalog Number: (75841-464)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells. JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Image Unavailable-75842-888

Anti-ITGB3 mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: VI-PL2]

Catalog Number: (75842-888)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
Image Unavailable-75843-602

Anti-Ly-6A/E Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: D7]

Catalog Number: (75843-602)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The D7 monoclonal antibody specifically reacts with mouse Ly-6A/E (Sca-1), a 18 kDa GPI-linked surface protein. It is expressed on multipotent hematopoietic stem cells (HSC) and subsets of B and T cells and involved in B and T cell lymphocyte responses. Splenocytes from Ly-6.2 strains exhibit a larger number of D7-positive cells than those from the Ly-6.1 strains.
Image Unavailable-75843-216

Anti-OX40L Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: RM134L]

Catalog Number: (75843-216)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
Image Unavailable-75843-172

Anti-CD197 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 3D12]

Catalog Number: (75843-172)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.

We recommend that this antibody be incubated for at least 45 minutes at 4°C for optimal staining.
Image Unavailable-75843-118

Anti-CD69 Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: H1.2F3]

Catalog Number: (75843-118)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Image Unavailable-75843-534

Anti-TER-119 Rat Monoclonal Antibody [clone: TER-119]

Catalog Number: (75843-534)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells.
Image Unavailable-75844-412

Anti-CD146 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: P1H12]

Catalog Number: (75844-412)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.
Image Unavailable-75843-032

Anti-CD5 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: UCHT2]

Catalog Number: (75843-032)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.
Image Unavailable-75842-918

Anti-CD3 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: OKT3]

Catalog Number: (75842-918)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
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