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Anti-IL-4 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: MP4-25D2]

Description: The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.
Catalog Number: 75843-526
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CSF1R Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: AFS98]

Description: The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Catalog Number: 75842-344
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CSF1R Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: AFS98]

Description: The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Catalog Number: 75842-334
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD154 Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: MR1]

Description: The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Catalog Number: 75842-302
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD45RA Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: HI100]

Description: The HI100 monoclonal antibody specifically reacts with human CD45RA, the 220 kDa isoform of the human leukocyte common antigen (LCA) found on 40-50% of the peripheral CD4+ T lymphocytes, half of the peripheral CD8+ T lymphocytes and some of the monocytes and B lymphocytes. The CD45RA antigen is expressed by naïve and activated T lymphocytes. The HI100 monoclonal antibody is used as a phenotypic marker to discriminate T lymphocytes subsets.
Catalog Number: 75844-124
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-PECAM1 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: WM59]

Description: The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Catalog Number: 75841-600
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-PECAM1 Mouse Monoclonal Antibody [clone: WM59]

Description: The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Catalog Number: 75841-588
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD20 Rat Monoclonal Antibody [clone: AISB12]

Description: The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
Catalog Number: 75842-748
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD20 Rat Monoclonal Antibody [clone: AISB12]

Description: The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
Catalog Number: 75842-746
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD11c Mouse Monoclonal Antibody (BG Violet 450) [clone: 3.9]

Description: The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin α chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Catalog Number: 75842-814
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD11c Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 3.9]

Description: The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin α chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Catalog Number: 75842-822
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-TLR4 Rat Monoclonal Antibody [clone: MTS510]

Description: The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex. The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The epitope that binds the MTS510 antibody is lost after LPS stimulation and the antibody can be used to co-immunoprecipitates MD-2 and TLR4.
Catalog Number: 75842-524
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-IL-2 Rat Monoclonal Antibody (Biotin) [clone: JES6-5H4]

Description: The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells. JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Catalog Number: 75841-458
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-PECAM1 Rat Monoclonal Antibody [clone: 390]

Description: The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1). CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Catalog Number: 75841-602
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CSF1R Rat Monoclonal Antibody [clone: AFS98]

Description: The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Catalog Number: 75842-330
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD172a Rat Monoclonal Antibody [clone: P84]

Description: The P84 monoclonal antibody specifically reacts with mouse CD172a, a type I transmembrane protein otherwise known as the signal-regulatory protein alpha. It is an adhesion molecules expressed on dendritic cells, monocytes, macrophages, and neuronal tissue. It is reported to be involved in regulating the phagocytic activity of macrophages and mediating neural synaptic activity. The P84 antibody is reported to have neutralizing capability.
Catalog Number: 75842-256
Supplier: BIOGEMS INTERNATIONAL INC.
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