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Anti-CD27 Armenian Hamster Monoclonal Antibody [clone: LG.7F9]

Catalog Number: (75842-018)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.7F9 antibody is cross-reactive human, mouse, and rat CD27.
Image Unavailable-75842-162

Anti-ITGB1 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: TS2/16]

Catalog Number: (75842-162)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA-(1-6) molecules with integrin alpha-(1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.
Image Unavailable-75842-298

Anti-CD40LG Armenian Hamster Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: MR1]

Catalog Number: (75842-298)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Image Unavailable-75842-278

Anti-CD144 (VE-Cadherin) Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 16B1]

Catalog Number: (75842-278)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 16B1 monoclonal antibody specifically reacts with human CD144, the 140 kDA molecule called vascular endothelial (VE-cadherin) or cadherin 5. CD144 is an endothelial specific calcium-dependent adhesion molecule involved in cell contact-dependent growth inhibition, migration, survival, adhesion. It is concentrated at the intercellular boundaries of endothelial cells and essential in maintaining cell layer integrity.
Image Unavailable-75842-598

Anti-Foxp3 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 3G3]

Catalog Number: (75842-598)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy” mice phenotype.
Image Unavailable-75842-600

Anti-Foxp3 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 3G3]

Catalog Number: (75842-600)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy” mice phenotype.
Image Unavailable-75842-156

Anti-CD19 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: HIB19]

Catalog Number: (75842-156)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The HIB19 monoclonal antibody specifically reacts with human CD19, a 95kDA type 1 transmembrane glycoprotein also known as B4. It is expressed on all stages of B cell development except for final plasma cells and on follicular dendritic cells. CD19 plays a role in B cell proliferation, activation, and differentiation. It functions as a BCR co-receptor with CD21 and CD81.
Image Unavailable-75843-648

Anti-IL-2 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: JES6-5H4]

Catalog Number: (75843-648)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells. JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Image Unavailable-75842-374

Anti-TLR4 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: HTA125]

Catalog Number: (75842-374)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
Image Unavailable-75843-530

Anti-IL-4 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: MP4-25D2]

Catalog Number: (75843-530)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.
Image Unavailable-75842-812

Anti-CD11c Mouse Monoclonal Antibody [clone: 3.9]

Catalog Number: (75842-812)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin α chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Image Unavailable-75842-856

Anti-PECAM1 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: 390]

Catalog Number: (75842-856)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1). CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
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Anti-CD11c Mouse Monoclonal Antibody (BG Violet 450) [clone: 3.9]

Catalog Number: (75842-816)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin α chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Image Unavailable-75842-336

Anti-CSF1R Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: AFS98]

Catalog Number: (75842-336)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
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Anti-Foxp3 (3G3) Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 3G3]

Catalog Number: (75842-604)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy” mice phenotype.
Image Unavailable-75843-796

Anti-CD2 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: RM2-5]

Catalog Number: (75843-796)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The RM2-5 monoclonal antibody specifically binds to mouse CD2, a member of the Ig superfamily and type I transmembrane glycoprotein. CD2 is expressed on B cells, T cells, NK cells, and thymocytes and its ligand is CD48. It may be involved in immunoregulation, thymocyte maturation, and T-cell activation. The RM2-5 antibody has been reported to block CD2 mediated cell to cell adhesion.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
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