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Product Image-10217-328

Burets, Automatic, Dr Schilling Pattern, Schellbach, Bürkle

Supplier: BURKLE INC
Description: Burette with Schellbach stripes type Schilling / Bürklewith original Bürkle dosing armature. A universal aid in the laboratory, electroplating industry, water treatment plants, for field analyses, etc. Precise dosing using the press button, exact fine titration with the micro-screw and precise discharge jet.

Image Unavailable-B-4230.0005BA

Fmoc-Tyr(So2(Oneopentyl))-Oh

Supplier: Bachem Americas
Description: Fmoc-Tyr(SO₃nP), a protected derivative of sulfotyrosine. The neopentyl ester is stable under the conditions of Fmoc-SPPS including the TFA-cleavage, but can be removed by treatment with aqueous ammonium acetate or sodium acetate. Thus, premature loss of sulfate groups during the final deprotection is prevented.

Product Image-10797-758

Human Recombinant PD14 (from HEK293 Cells)

Catalog Number: (10797-758)
Supplier: Prosci
Description: Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-?. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-? by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-? secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
Image Unavailable-75912-080

Anti-ICAM3 Mouse Monoclonal Antibody [clone: ICAM3/1019]

Catalog Number: (75912-080)
Supplier: Biotium
Description: This antibody recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
Image Unavailable-H-7435.0001BA

Acetyl-Hirudin (55-65) (Sulfated)

Catalog Number: (H-7435.0001BA)
Supplier: Bachem Americas
Description: These peptides correspond to the C-terminus of the 65-residue polypeptide hirudin, a potent thrombin inhibitor found in the saliva of the leech Hirudo medicinalis. Treatment of hirudin with carboxypeptidase Y has shown that the last 5 amino acids are essential for its inhibitory activity.
Product Image-89157-842

(R)-(-)-Deprenyl hydrochloride ≥98% (by HPLC)

Catalog Number: (89157-842)
Supplier: Enzo Life Sciences
Description: Deprenyl inhibits apoptosis and displays neuroprotective effects in a variety of in vitro and in vivo systems. In vivo it rescues nigral dopaminergic neurons after systemic MPTP treatment. In vitro it rescues PC12 cells from apoptotic cell death induced by trophic withdrawal. The putative target responsible for the anti-apoptotic effects is glyceraldehyde-3-phosphate dehydrogenase. Deprenyl also inhibits monoamine oxidase-B, which is not involved in its anti-apoptotic mechanism. Parkinson’s disease therapeutic.
Image Unavailable-H-7344.0005BA

H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH Trifluoroacetate

Catalog Number: (H-7344.0005BA)
Supplier: Bachem Americas
Description: CALP-3, VKFGVGFK, acts as a calmodulin agonist. The octapeptide interacts with the calmodulin EF-hand motif, the Ca²⁺-binding site. CALP-3 activates phosphodiesterase in the absence of calcium and inhibits Ca²⁺-mediated cytotoxicity and apoptosis. CALP-3 is more active than CALP-1 (H-8155), By preventing trypsin activation within pancreatiic acinar cells CALP-3 shows potential therapeutic potential in the treatment of pancreatitis.
Product Image-76424-378

Spotsee Forehead Thermometer Temperature Strip, Propper

Catalog Number: (76424-378)
Supplier: Propper
Description: During any illness outbreak, early fever detection not only helps prevent the spread of illnesses, it also ensures faster treatment. Liquid crystal technology-based, an FDA registered forehead thermometer provide a simple, cost-effective tool for monitoring body temperature.
Image Unavailable-77007-476

Anti-Bevacizumab Mouse Monoclonal Antibody [clone: 11C1]

Catalog Number: (77007-476)
Supplier: Genscript
Description: Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of a number of types of cancers and a specific eye disease. Bevacizumab binds to a continuous epitope in VEGF, preventing interaction of VEGF with VEGFR on the surface of endothelial cells. It can be used to inhibit solid tumours growth and metastasis by weakening tumour angiogenesis.
Product Image-10822-048

Human Recombinant IFNalpha 2b (from E. coli)

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Interferon-alpha 2b (IFN-α2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α2b. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α2b variant differs from IFN-α2a by one amino acid.

Product Image-470315-142

Stem Investigations: Design a Water Filter

Catalog Number: (470315-142)
Supplier: Ward's Science
Description: How is the water that comes out of our faucets made safe for consumption?
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Galanin (1-13)-Bradykinin (2-9) amide

Supplier: Bachem Americas
Description: The galanin antagonist M35, which binds with high specificity and affinity to galanin binding sites, has been administered to rats to test the functional consequences of the galanin receptor blockade in a spatial learning task. The results suggest that galanin antagonists might provide a new principle in the treatment of dementia and related disorders. M35 (but not M40 or C7) ameliorated cerulein-induced acute pancreatitis in mice.

Product Image-CA89500-668

Tannin/Lignin Test Kit, Hach

Supplier: Hach
Description: A product of decomposed plant material, tannin occurs in natural waters and is used for boiler and cooling tower water treatment, dyeing, ink manufacture, tanning, and paper sizing

SDS

Product Image-76516-456

PURELAB® Chorus 3 Water Purification System, ELGA LabWater

Catalog Number: (76516-456)
Supplier: ELGA LabWater
Description: When general laboratory grade water (Type III) is all you need, then PURELAB Chorus 3 is the reliable solution with the flexibility to suit your requirements.
Product Image-CA89020-078

A800 Series Protective Eyewear, Honeywell Safety

Supplier: Honeywell Safety Products
Description: Stylish, sporty, and economic A800 series eyewear provides fashionable protection for the everyday wearer.

Image Unavailable-H-4060.0005BA

(Des-Gly¹⁰,D-Leu⁶,Pro-NHEt⁹)-LHRH Acetate

Supplier: Bachem Americas
Description: LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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