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Human Recombinant Cardiotrophin 1 (from E. coli)

Catalog Number: (10072-876)
Supplier: Prosci
Description: CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Recombinant Human CT-1 is a 21.5 kDa protein consisting of 201 amino acid residues.
Image Unavailable-75966-682

Anti-ODC1 Mouse Monoclonal Antibody (Biotin) [clone: ODC1/486]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Image Unavailable-10072-584

Mouse Recombinant RELM alpha (from E. coli)

Catalog Number: (10072-584)
Supplier: Prosci
Description: RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown. Recombinant murine RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.
Image Unavailable-75791-770

Mouse Recombinant Frizzled 2

Catalog Number: (75791-770)
Supplier: Prosci
Description: Wnt signaling plays a critical role in embryonic development, and genetic aberrations. Frizzled2 (Fzd2) is a receptor for wingless-type MMTV integration site family members (Wnts), the aberrant overexpression of which has been noted to contribute to cancer metastasis. Frizzled2 (Fzd2) and its ligands Wnt5a/b are elevated in metastatic liver, lung, colon, and breast cancer cell lines and in high-grade tumors and that their expression correlates with markers of epithelial-mesenchymal transition (EMT). It is also shown that Frizzled-2 expression is greater in embryonic than adult tissues, with heart, brain, lung, kidney and gut showing the highest levels.
Image Unavailable-10372-688

Anti-Rb/P105 RB Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10372-688)
Supplier: Bioss
Description: Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Image Unavailable-CA82021-800

Mammalian GenLysate™ Human Total Protein Lysates, G-Biosciences

Catalog Number: (CA82021-800)
Supplier: G-Biosciences
Description: G-Biosciences GenLysate™ total protein lysates are ready to use for SDS-PAGE and Western blotting purposes.
Product Image-10369-302

Anti-RB1 Rabbit Polyclonal Antibody

Catalog Number: (10369-302)
Supplier: Bioss
Description: Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Image Unavailable-10482-382

Anti-FGFR1OP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10482-382)
Supplier: Bioss
Description: FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
Image Unavailable-CA82022-344

Mammalian GenLysate™ Human Total Protein Lysates, Tumor Tissue, G-Biosciences

Catalog Number: (CA82022-344)
Supplier: G-Biosciences
Description: G-Biosciences' GenLysate™ total protein lysates are ready to use for SDS-PAGE and Western blotting purposes.
Image Unavailable-TCA2509-VIAL

Anti-SLeA Mouse Monoclonal Antibody [clone: 2D3]

Catalog Number: (TCA2509-VIAL)
Supplier: TCI America
Description: Purified mouse monoclonal antibody/IgM, κ-chain

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Image Unavailable-75788-932

Human Recombinant beta-Defensin 1 (from E. coli)

Catalog Number: (75788-932)
Supplier: Prosci
Description: beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.
Image Unavailable-75966-756

Anti-ODC1 Mouse Monoclonal Antibody (Biotin) [clone: ODC1/487]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Image Unavailable-75966-636

Anti-ODC1 Mouse Monoclonal Antibody (Biotin) [clone: ODC1/485]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Image Unavailable-75966-664

Anti-ODC1 Mouse Monoclonal Antibody [clone: ODC1/485]

Catalog Number: (75966-664)
Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
Image Unavailable-75966-670

Anti-ODC1 Mouse Monoclonal Antibody [clone: ODC1/486]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Product Image-76186-226

Hydrogen peroxide 30 - 32%, ARISTAR® ULTRA, Ultrapure for trace metal analysis, VWR Chemicals BDH®

Supplier: BDH
Description: Ultra high purity acid for quantitative trace metal analysis at the parts-per-trillion (ppt) level.

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