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Catalog Number: (89416-942)
Supplier: Prosci
Description: KCTD15 Antibody: Childhood and adult obesity in the United States and to a lesser extent the rest of the world has increased dramatically over the past decade. Both environmental and genetic factors are involved in the onset and progression of weight gain. Recently, the potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Further studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. At least two isoforms of KCTD15 are known to exist.


Catalog Number: (10425-630)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).


Catalog Number: (CA607-101-130)
Supplier: Rockland Immunochemical
Description: Secondary Goat Anti-IgG (H&L) Reacts with Hamster


Catalog Number: (CA213-4107)
Supplier: Rockland Immunochemical
Description: Secondary Rabbit Anti-IgM mu chain Reacts with Sheep (Ovine)


Catalog Number: (10425-628)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).


Catalog Number: (10425-632)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).


Catalog Number: (10101-778)
Supplier: Prosci
Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ16 is an integral membrane protein and inward-rectifier type potassium channel. KCNJ16, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.


Catalog Number: (76078-668)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).


Catalog Number: (10425-626)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).


Catalog Number: (10425-574)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).


Catalog Number: (10089-264)
Supplier: Proteintech
Description: KCNJ2, also named as HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7 and SQT3, belongs to the inward rectifier-type potassium channel family. KCNJ2 probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ2 can be blocked by extracellular barium or cesium. Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7). Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3). The antibody recognizes the C-term of KCNJ2.


Supplier: VWR
Description: This general-purpose water is purified by deionization. Water has a pH of 5.0 to 7.0. It passes the test for reducing potassium permanganate.
Catalog Number: (77438-092)
Supplier: Bioss
Description: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.


Catalog Number: (10350-338)
Supplier: Bioss
Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.


Catalog Number: (10350-340)
Supplier: Bioss
Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.


Catalog Number: (CA604-1103)
Supplier: Rockland Immunochemical
Description: Secondary Goat Anti-IgG F(c) Reacts with Dog (Canine)


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