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Image Unavailable-10338-534

Anti-ARHGEF2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10338-534)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
Image Unavailable-10338-536

Anti-ARHGEF2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10338-536)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
Image Unavailable-76083-798

Anti-MYPT1 Ser507 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76083-798)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene.
Product Image-76701-736

Human Rho GDP-dissociation Inhibitor 2 (ARHGDIB) ELISA Kit

Catalog Number: (76701-736)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968
Product Image-77524-502

Human Rock2 (Rho Associated Coiled Coil Containing Protein Kinase 2) ELISA Kit

Catalog Number: (77524-502)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968

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Image Unavailable-10338-528

Anti-ARHGEF2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10338-528)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
Image Unavailable-10366-770

Anti-PPP1R12A Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10366-770)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Image Unavailable-76630-562

Anti-RHO Recombinant Antibody [Clone: Rho 1D4]

Catalog Number: (76630-562)
Supplier: Prosci
Description: 31472488
Product Image-76702-550

Mouse Rho-associated Protein Kinase 2(ROCK2) ELISA Kit

Catalog Number: (76702-550)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968
Product Image-76714-838

Human Rho GTPase-activating Protein 9 (ARHGAP9) ELISA Kit

Catalog Number: (76714-838)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968
Image Unavailable-77440-660

Anti-DIAPH3 Rabbit Polyclonal Antibody

Catalog Number: (77440-660)
Supplier: Bioss
Description: Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.
Image Unavailable-10452-880

Anti-TIAM1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10452-880)
Supplier: Bioss
Description: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
Image Unavailable-10423-514

Anti-ARHGAP24 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (10423-514)
Supplier: Bioss
Description: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Product Image-10814-104

Anti-DPYSL2 Rabbit Polyclonal Antibody

Catalog Number: (10814-104)
Supplier: Prosci
Description: CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Image Unavailable-76101-744

Anti-GEF H1 Ser886 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-744)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
Product Image-76711-638

Human Rho GTPase-activating Protein 22 (ARHGAP22) ELISA Kit

Catalog Number: (76711-638)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968
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