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Product Image-CA10016-104

Dupont™ ProShield® 60 Coveralls with Standard Hood and Attached Skid Resistant Boots

Catalog Number: (CA10016-104)
Supplier: DuPont
Description: ProShield® 60 garments are suitable for protection against non-hazardous particles, light liquid splash and aerosols in many industrial applications.
Product Image-76421-948

Table-Gard Disposable Work Mats, Orange, Accuform

Supplier: ACCUFORM MANUFACTURING, INC
Description: Create safe, clean workspaces by applying the adhesive mat to surfaces that are not regularly cleaned.

Image Unavailable-80093-280

AlphaTec™ 56-101 Heavy-Duty PVC Aprons, Ansell

Supplier: Ansell Healthcare
Description: These heavy-duty PVC aprons feature 18-millimeter die-cut PVC and offer users a combination of chemical splash protection and flexible comfort.

Product Image-89092-152

BinLiners and BinLiner Stands, Micronova

Supplier: Micronova
Description: The LDPE Micronova BinLiners™ are ideal for the collection and disposal of waste, collection and transportation of parts or raw materials, and storage in cleanrooms and controlled environments. Thickness of 1 to 6 mm available for a variety of applications; including covering equipment, holding production waste, document storage, lining large production totes and so on.

Certificates Small Business Enterprise Minority or Woman-Owned Business Enterprise

Product Image-76421-888

Table-Gard Disposable Work Mats, Beach Waves, Accuform

Supplier: ACCUFORM MANUFACTURING, INC
Description: Create safe, clean workspaces by applying the adhesive mat to surfaces that are not regularly cleaned.

Product Image-100496-238

Reticles with Frame, Electron Microscopy Sciences

Catalog Number: (100496-238)
Supplier: Electron Microscopy Sciences
Description: Reticle A is designed for general laboratory use (5 mm long, with 0.1 mm divisions) and reticle B (<sup>4</sup>/<sub>16</sub> " long, <sup>1</sup>/<sub>64</sub>" divisions) is most frequently used in textiles or electronics, and where measurement in mils is required. Reticle C (5000 µm long, with 50 µm divisions) is calibrated in microns and helpful for pesticide droplet size measurements or anywhere measurements in microns are required.

Minority or Woman-Owned Business Enterprise


Image Unavailable-80093-282

AlphaTec™ 56-102 Heavy-Duty PVC Aprons, Ansell

Catalog Number: (80093-282)
Supplier: Ansell Healthcare
Description: These heavy-duty PVC aprons feature die-cut PVC and offer users a combination of chemical splash protection and flexible comfort. The 56-102 aprons have an additional 18-millimeter patch in the stomach area in order to provide extra protection in the critical high wear areas. 48" ties and sealed grommets provide a durable, consistent and adjustable fit. Bib styles in two sizes with adjustable ties ensure optimal fit for a wide range of users.
Product Image-10061-908

Anti-BRAF Rabbit Polyclonal Antibody

Catalog Number: (10061-908)
Supplier: Prosci
Description: B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.
Product Image-89417-480

Anti-B-RAF Chicken Polyclonal Antibody

Catalog Number: (89417-480)
Supplier: Prosci
Description: B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.
Product Image-10751-984

Anti-BRAF Rabbit Polyclonal Antibody

Catalog Number: (10751-984)
Supplier: Prosci
Description: B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.
Image Unavailable-75791-070

Mouse Recombinant IL13 (from E. coli)

Catalog Number: (75791-070)
Supplier: Prosci
Description: Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13R alpha1 with low affinity and triggers association of IL4R alpha, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13R alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
Product Image-10750-968

Anti-BRAF Chicken Polyclonal Antibody

Catalog Number: (10750-968)
Supplier: Prosci
Description: B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.
Image Unavailable-75790-492

Mouse Recombinant IL13

Catalog Number: (75790-492)
Supplier: Prosci
Description: Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13R alpha1 with low affinity and triggers association of IL4R alpha, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13R alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
Image Unavailable-75790-490

Mouse Recombinant IL13

Catalog Number: (75790-490)
Supplier: Prosci
Description: Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13R alpha1 with low affinity and triggers association of IL4R alpha, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13R alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
Image Unavailable-75788-868

Mouse Recombinant IL13 (from E. coli)

Catalog Number: (75788-868)
Supplier: Prosci
Description: Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13R alpha1 with low affinity and triggers association of IL4R alpha, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13R alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
Image Unavailable-MSPP-780831006

Human Recombinant IL-6R alpha

Catalog Number: (MSPP-780831006)
Supplier: STEMCELL Technologies
Description: Interleukin 6 receptor (IL-6R) alpha is a type I transmembrane glycoprotein that forms a complex with type I transmembrane signal transducer protein gp130 (CD130) and mediates the biological activities of IL-6. IL-6 binds to the membrane-bound non-signaling IL-6R alpha (mIL-6R), and the complex binds to two molecules of gp130 and leads to ‘classical’ IL-6-signal transduction, which includes activation of JAK/STAT, ERK, and PI3K signal transduction pathways (Scheller <i>et al.</i>). In contrast, a soluble form of IL-6R alpha (sIL-6R), which comprises the extracellular portion of the receptor, binds to the secreted IL-6 to form a complex that promotes bioavailability of IL-6. The complex of IL-6 and sIL-6R can bind to gp130 on cells that do not express the IL-6R and are unresponsive to IL-6. This process is known as trans-signaling (Hunter and Jones; Rose-John S). sIL-6R regulates both local and systemic IL-6-mediated events. Elevated levels of sIL-6R have been documented in several disease conditions such as rheumatoid arthritis, myeloma, and Crohn’s disease (Jones <i>et al.</i>; Mihara <i>et al.</i>).

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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