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Image Unavailable-89151-518

8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate triethylammonium salt ≥99% (by HPLC)

Catalog Number: (89151-518)
Supplier: Enzo Life Sciences
Description: Activator of PKG and CNG channels.
Product Image-89151-582

8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate sodium salt ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels.

Product Image-89157-032

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer triethylammonium salt ≥98% (by HPLC)

Catalog Number: (89157-032)
Supplier: Enzo Life Sciences
Description: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS
Product Image-89157-010

8-(4-Chlorophenylthio)adenosine-3',5'-cyclic monophosphate sodium salt (synthetic) ≥96% (by HPLC)

Supplier: Enzo Life Sciences
Description: PKA activator.

Product Image-89151-520

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer triethylammonium salt ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

Product Image-89151-588

8-(4-Chlorophenylthio)-2'-O-methyladenosine-3’,5’-cyclic monophosphate sodium salt ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: Specific, potent and membrane permeant activator of the Epac cAMP receptor.

Product Image-76578-638

Rat Cyclic Guanosine Monophosphate (cGMP) ELISA Kit, AFG Bioscience

Catalog Number: (76578-638)
Supplier: AFG BIOSCIENCE LLC
Description: Rat Cyclic Guanosine Monophosphate (cGMP) ELISA Kit, AFG Bioscience
Image Unavailable-77538-446

General Cyclic Guanosine Monophosphate (cGMP) ELISA Kit

Catalog Number: (77538-446)
Supplier: Bioss
Description: General Cyclic Guanosine Monophosphate (cGMP) ELISA Kit

New Product


Product Image-76703-460

Human Cyclic Guanosine Monophosphate (cGMP) ELISA Kit

Catalog Number: (76703-460)
Supplier: AFG BIOSCIENCE LLC
Description: Human Cyclic Guanosine Monophosphate (cGMP) ELISA Kit
Product Image-77525-550

cGMP (Cyclic Guanosine Monophosphate) ELISA Kit

Catalog Number: (77525-550)
Supplier: AFG BIOSCIENCE LLC
Description: cGMP (Cyclic Guanosine Monophosphate) ELISA Kit

New Product


Product Image-77526-378

Human cGMP (Cyclic Guanosine Monophosphate) ELISA Kit

Catalog Number: (77526-378)
Supplier: AFG BIOSCIENCE LLC
Description: Human cGMP (Cyclic Guanosine Monophosphate) ELISA Kit

New Product


Image Unavailable-CA80051-960

Guanosine-3',5'-cyclicmonophosphoric acid sodium salt

Catalog Number: (CA80051-960)
Supplier: MilliporeSigma
Description: Guanosine 3'',5''-cyclic Monophosphate, Sodium. (cyclic GMP; G-3,5-MP; cGMP, sodium). White solid. Important intracellular messenger implicated in the action of nitric oxide in many cell types. Activates protein kinase G.

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Image Unavailable-76085-276

Anti-cGMP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76085-276)
Supplier: Bioss
Description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Image Unavailable-76085-278

Anti-cGMP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76085-278)
Supplier: Bioss
Description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Image Unavailable-89367-374

Anti-PDE5A Rabbit Polyclonal Antibody

Catalog Number: (89367-374)
Supplier: Genetex
Description: The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of G protein coupled receptors (GPCRs) for hormones, cytokines, and neurotransmitters. Cyclic nucleotides are important intracellular second messengers which play important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. One of the many phosphodiesterases that compartmentalized and hydrolyze cGMP in various tissues is phosphodiesterase type 5A. The cGMP is involved in nitric oxide signaling as well as cell signaling associated with natriuretic peptides and gulanylins. Some of the intracellular biding cites for the cGMP include cyclic nucleotide gated ion channels, cGMP dependent protein kinases, and cyclic GMP biding phosphodiesterases (cGB PDEs). The cGB PDEs include PDE2, PDE3, PDE5, PDE5 and PDE10; the members of these families contain various structural and functional motifs that are conserved. Most of these proteins contain dimmeric subunits that contain a highly conserved cGMP binding site and a phosphodiesterase catalytic site.
Image Unavailable-10389-406

Anti-cGMP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10389-406)
Supplier: Bioss
Description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
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