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Image Unavailable-76109-900

Anti-AGXT2L2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76109-900)
Supplier: Bioss
Description: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
Image Unavailable-EM8.18367.0001

L-(-)-tert-Leucine (H-Tle-OH) for synthesis, Sigma-Aldrich®

Catalog Number: (EM8.18367.0001)
Supplier: MilliporeSigma

SDS


Image Unavailable-10428-632

Anti-RBBP5 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10428-632)
Supplier: Bioss
Description: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Image Unavailable-10428-638

Anti-RBBP5 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10428-638)
Supplier: Bioss
Description: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Image Unavailable-10166-878

Anti-HIST1H4A Rabbit Polyclonal Antibody

Catalog Number: (10166-878)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to Histone H4 (tri methyl Lys20) (histone cluster 1, H4a)
Image Unavailable-10406-526

Anti-ACAT1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10406-526)
Supplier: Bioss
Description: This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009].
Image Unavailable-89139-064

Propidium iodide

Catalog Number: (89139-064)
Supplier: Biotium
Description: Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.

Certificates


Image Unavailable-TCB3193-5G

Coomassie brilliant blue G-250

Catalog Number: (TCB3193-5G)
Supplier: TCI America
Description: CAS Number: 6104-58-1
MDL Number: MFCD00078482
Molecular Formula: C47H48N3NaO7S2
Molecular Weight: 854.02
Form: Crystal
Color: Red

SDS Certificates


Image Unavailable-10167-746

Anti-HIST1H3A Mouse Monoclonal Antibody [clone: MABI0333]

Catalog Number: (10167-746)
Supplier: Genetex
Description: Mouse Monoclonal antibody [MABI0333] to Histone H3 (tri-methyl Lys36)
Product Image-10100-318

Anti-ETFA Rabbit Polyclonal Antibody

Catalog Number: (10100-318)
Supplier: Prosci
Description: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Image Unavailable-10167-588

Anti-HIST1H4A Mouse Monoclonal Antibody [clone: GT282]

Catalog Number: (10167-588)
Supplier: Genetex
Description: Mouse Monoclonal antibody [GT282] to Histone H4 (di methyl Lys20) (histone cluster 1, H4a)
Product Image-10102-584

Anti-HAAO Rabbit Polyclonal Antibody

Catalog Number: (10102-584)
Supplier: Prosci
Description: 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
Product Image-CABJ015-4

Acetonitrile ≥99.9%, B&J Brand™, gradient grade for HPLC, for pesticide residue analysis, for spectrophotometry, Burdick & Jackson™

Supplier: Burdick & Jackson
Description: For HPLC, liquid and gas chromatography, pesticide residue analysis, spectophotometry, organic synthesis and combinatorial chemistry.

SDS Certificates

Product Image-89358-192

Anti-TIG1 Rabbit Polyclonal Antibody

Catalog Number: (89358-192)
Supplier: Genetex
Description: This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq]
Image Unavailable-TCM2526-5G

Monomethyl-trans-1,4-cyclohexanedicarboxylate ≥97.0% (by GC, titration analysis)

Supplier: TCI America
Description: CAS Number: 15177-67-0
MDL Number: MFCD01311247
Molecular Formula: C9H14O4
Molecular Weight: 186.21
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Melting point (°C): 128

SDS

Image Unavailable-10406-512

Anti-ACAT1 Rabbit Polyclonal Antibody

Catalog Number: (10406-512)
Supplier: Bioss
Description: This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009].
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