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Product Image-CAMK258012

EDTA (ethylenediamine tetraacetic acid) 99.4-100.6%, powder, AR® ACS, Macron Fine Chemicals™

Catalog Number: (CAMK258012)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Powder.

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Image Unavailable-10773-604

Human Recombinant TPO (from E. coli)

Supplier: Peprotech
Description: TPO is a lineage-specific growth factor produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo . TPO signals through the c-mpl receptor, and acts as an important regulator of circulating platelets. Human and murine TPO exhibit cross-species reactivity. The human TPO gene encodes for a 353 amino acid glycoprotein, which contains a 21 amino acid signal sequence, a 15 amino acid erythropoietin-like domain, and a highly glycosylated 179 amino acid C-terminal domain. Recombinant Human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

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Product Image-77518-238

Human EAAT4 (Excitatory Amino Acid Transporter 4) ELISA Kit

Catalog Number: (77518-238)
Supplier: AFG Bioscience
Description: Human EAAT4 (Excitatory Amino Acid Transporter 4) ELISA Kit
Image Unavailable-10772-476

Human;Mouse;Rat Recombinant GDF-11 (fromE. coli)

Supplier: Peprotech
Description: GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves the arrest of the progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggest that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant Human/Murine/Rat GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8, sharing 90% amino acid sequence identity.

Image Unavailable-10073-044

Human Recombinant SCD30 Ligand (from CHO Cells)

Catalog Number: (10073-044)
Supplier: Prosci
Description: CD30 ligand (CD30L) is a type-II membrane-associated glycoprotein protein belonging to the TNF superfamily and is expressed primarily on certain B cells, T cells, and monocytes. CD30L binds specifically to CD30 (receptor), which is expressed on activated, but not resting, B and T cells, in lymphomas and various chronically inflamed tissues. CD30L/CD30 interactions initiate a signaling cascade that can ultimately lead to the activation of NF-KappaB. CD30L/CD30 signaling exerts pleiotropic effects on normal cells, including cell death, differentiation, or cell division. Certain diseases, including Hodgkins’s lymphoma, allergic inflammation, diabetes (in NOD mice), and mycobacterial infection can also be affected by CD30L/CD30 signaling. The CD30L gene encodes for a 234 amino acid type II transmembrane protein, which contains a 37 amino acid cytoplasmic sequence, a 25 amino acid transmembrane domain and a 172 amino acid extracellular domain. Recombinant human soluble CD30L (sCD30L) is a 188 amino acid polypeptide corresponding to the extracellular domain, and contains an 8 residue N-terminal His -Tag.
Image Unavailable-75789-750

Human Recombinant IL-20 R alpha (from Cells)

Catalog Number: (75789-750)
Supplier: Prosci
Description: Interleukin-20 Receptor Subunit alpha (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
Image Unavailable-10062-666

Human PTRF Peptide

Catalog Number: (10062-666)
Supplier: Prosci
Description: 19 amino acid peptide near the carboxy terminus of human PTRF.
Product Image-10102-000

Anti-TULP3 Rabbit Polyclonal Antibody

Catalog Number: (10102-000)
Supplier: Prosci
Description: TULP3 is a member of the tubby-like protein (TULP) family. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved C-terminal region of approximately 200 amino acid residues. The human and mouse TULP3 proteins share 69% amino acid sequence identity, with higher identity at the N and C termini than in the central region.This gene encodes a member of the tubby-like protein (TULP) family. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved C-terminal region of approximately 200 amino acid residues. The human and mouse TULP3 proteins share 69% amino acid sequence identity, with higher identity at the N and C termini than in the central region.
Product Image-77975-381

L-Glutamine solution 200 mM 29.2 mg/ml

Supplier: FUJIFILM IRVINE SCIENTIFIC INC.
Description: <p>An essential amino acid important for cellular growth. Unstable at physiological pH.</p>

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Image Unavailable-10488-052

Anti-AMPK gamma 1/2/3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10488-052)
Supplier: Bioss
Description: AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein. The human AMPKg1 gene encodes a 331 amino acid protein. Human AMPKg2 and AMPKg3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.
Product Image-10061-742

Human CARM1 Peptide

Catalog Number: (10061-742)
Supplier: Prosci
Description: 19 amino acids near the amino terminus of human CARM1.
Product Image-CAJT3605-6

Sodium carbonate, anhydrous 99.5-100.5% (by anhydrous basis), granular NF, FCC, J.T.Baker®

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: pH adjusters are used to adjust the pH of formulations.

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Image Unavailable-10088-186

Anti-ICAM3 Rabbit Polyclonal Antibody

Catalog Number: (10088-186)
Supplier: Proteintech
Description: Anti-ICAM3 Antibody, Host Species: Rabbit, Cross Reactivity: Human, Immunogen: Recombinant Protein, 200-547 amino acid amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower
Image Unavailable-10774-332

Mouse Recombinant HGF (from (BTI-Tn-5B1-4) Hi-5 Insect cells)

Supplier: Peprotech
Description: HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Murine HGF is expressed as a linear, polypeptide-precursor glycoprotein containing 696 amino acid residues. Proteolytic processing of this precursor generates the biologically active heterodimeric form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held together by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 233 amino acid residues. Recombinant Murine HGF is a 79.3 kDa polypeptide consisting of 696 amino acid residues.

Image Unavailable-10774-350

Mouse Recombinant GDF-5 (from E. coli)

Supplier: Peprotech
Description: GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities. The mature and functional form of GDF-5 is a homodimer of two 120 amino acid polypeptide chains (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 348 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant Murine GDF-5 (BMP-14/CDMP-1) is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.

Product Image-77975-363

Click's Medium (EHAA)

Catalog Number: (77975-363)
Supplier: FUJIFILM IRVINE SCIENTIFIC INC.
Description: Click's Medium is a modification of Eagle's Essential Medium with Hanks' Salts (HMEM) and contains higher concentrations of essential amino acids, in addition to non-essential amino acids, sodium pyruvate, and nucleic acid precursors.

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