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Description: Certain loci on human chromosome 17q12 are frequently amplified in various types of cancers. One of such loci is PP1R1B-ERBB2-GRB7 which is greatly amplified in gastric and breast cancer. Search of other genes that reside close to this recombination hot spot or ""fragile loci"" led to discovery of several genes, one of these genes is a new theoretical protein MGC14832 is localized on chromosome 17 at cytogenetic location of 17q21.2. The detailed analyses of the amplicon structure in 330 breast tumors samples revealed a 280 kb common region of amplification that contains 10 genes that include 8 known genes. A highly significant association between amplification and expression levels was observed for 6 genes including ERBB2 and 2 uncharacterized hypothetical proteins, MGC9753 and MGC14832, in breast carcinoma and human gastric cancer samples. MGC14832 is located on human chromosome 17q12 and is in the amplicon cluster consist of PPP1R1B-STARD3-TCAP-PNMT-MGC9753-ERBB2-MGC14832-GRB7 with in the 120 kb region locus on human chromosome 17q12.
Catalog Number: 89367-392
Supplier: Genetex


Description: Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: IHC-P, WB Pkg Size: 100 ul
Catalog Number: 89324-080
Supplier: Genetex


Description: Rabbit Polyclonal antibody to c-Yes (v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1)
Catalog Number: 89348-568
Supplier: Genetex


Description: Rabbit Polyclonal antibody to Periostin
Catalog Number: 89306-762
Supplier: Genetex


Description: Mouse monoclonal antibody [1A10] to GAPDH
Catalog Number: 89285-070
Supplier: Genetex


Description: Rabbit Polyclonal antibody to Cytokeratin 16 (keratin 16)
Catalog Number: 89318-316
Supplier: Genetex


Description: APC-conjugated Mouse Monoclonal antibody [HI149] to CD1a
Catalog Number: 89298-984
Supplier: Genetex


Description: Rabbit polyclonal antibody to RPS29 (N-terminal)
Catalog Number: 89288-914
Supplier: Genetex


Description: Rabbit polyclonal antibody to adenylate kinase 7 (adenylate kinase 7)
Catalog Number: 89320-824
Supplier: Genetex


Description: Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific "background" binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
Catalog Number: 89367-104
Supplier: Genetex


Description: Rat monoclonal antibody [ER-BMDM1] to CD13
Catalog Number: 89307-236
Supplier: Genetex


Description: Goat polyclonal antibody to ALDH1A1 (Internal)
Catalog Number: 89297-600
Supplier: Genetex


Description: Protein extract from Human Brain: Corpus Callosum (Alzheimer's Disease) Pkg Size: 200 ug
Catalog Number: 89322-290
Supplier: Genetex


Description: Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28, which displays chemotactic activity for resting CD4+ and CD8+ T cells.
Catalog Number: 89361-054
Supplier: Genetex


Description: Rabbit Polyclonal antibody to Pyruvate Kinase (liver/RBC) (pyruvate kinase, liver and RBC)
Catalog Number: 89356-766
Supplier: Genetex


Description: Rabbit polyclonal antibody to LPPR2 (Middle)
Catalog Number: 89268-406
Supplier: Genetex


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