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Image Unavailable-76100-934

Anti-GLUR4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.
Catalog Number: 76100-934
Supplier: Bioss
Image Unavailable-TCG0123-100MG

Glycyl-L-Glutamic Acid

Description: Melting point: 158 °C
Specific rotation [a]20/D: –7° (C=5, H₂O)
Water: Max. 8.0%
Purity (nonaqueous titration): Min. 98.0% (calculated on anhydrous substance)
Catalog Number: TCG0123-100MG
Supplier: TCI America

SDS


Product Image-10101-944

Anti-GRIK5 Rabbit Polyclonal Antibody

Description: GRIK5 is a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. GRIK5 forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number: 10101-944
Supplier: Prosci
Product Image-10109-238

Anti-SLC25A22 Rabbit Polyclonal Antibody

Description: The SLC25 family is mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane. SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18.The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).
Catalog Number: 10109-238
Supplier: Prosci
Image Unavailable-E-1895.0050BA

H-Glu(OBzl)-OBzl.TosOH

Description: Sequence: H-Glu(OBzl)-OBzl · p-tosylate
Catalog Number: E-1895.0050BA
Supplier: Bachem Americas
Product Image-10101-226

Anti-GRIK2 Rabbit Polyclonal Antibody

Description: The GRIK2 gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.
Catalog Number: 10101-226
Supplier: Prosci
Image Unavailable-76100-942

Anti-Group I mGLUR Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions.
Catalog Number: 76100-942
Supplier: Bioss
Image Unavailable-10167-618

Anti-GLUL Mouse Monoclonal Antibody [clone: GT7711]

Description: Mouse Monoclonal antibody [GT7711] to Glutamine synthetase (glutamate-ammonia ligase)
Catalog Number: 10167-618
Supplier: Genetex
Image Unavailable-76080-342

Anti-NMDAR2B Tyr1336 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Catalog Number: 76080-342
Supplier: Bioss
Image Unavailable-CAAAJ62777-MD

Ivermectin

Description: Antiparasitic and macrolide antibiotic. Modulates glutamate-GABA-activated chloride channels. Also activates the glycine receptor chloride channel
Catalog Number: CAAAJ62777-MD
Supplier: Thermo Scientific Chemicals

Certificates


Image Unavailable-89358-714

Anti-SLC25A22 Rabbit Polyclonal Antibody

Description: The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004 [PubMed 14598172]). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).[supplied by OMIM]
Catalog Number: 89358-714
Supplier: Genetex
Image Unavailable-89349-860

Anti-MGLUR5 Rabbit Polyclonal Antibody

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors (GPCRs) that contain 7 membrane-spanning domains and a large extracellular N-terminal region. The group I receptors mGluR1 and mGluR5 activate phospholipase C. By screening a human brain cDNA library with a rat mGluR1-alpha cDNA under low stringency conditions, Minakami et al. (1993) and Minakami et al. (1994) isolated human cDNAs encoding mGluR5. Minakami et al. (1993) identified a longer isoform of mGluR5 (mGluR5B).
Catalog Number: 89349-860
Supplier: Genetex
Image Unavailable-G-4590.0100BA

Ac-Asp(Glu-OH)-OH

Description: A non-hydrolyzable NAAG isomer which acts as selective metabotropic glutamate receptor-3 (mGluR3) antagonist and NAAG peptidase inhibitor.
Catalog Number: G-4590.0100BA
Supplier: Bachem Americas
Image Unavailable-77987-745

TRC (4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)(nitroso)amino)benzoyl-2,3,5,6-d4)glutamic Acid (1 mg/ml in DMSO)

Description: TRC (4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)(nitroso)amino)benzoyl-2,3,5,6-d4)glutamic Acid (1 mg/ml in DMSO)
Catalog Number: 77987-745
Supplier: LGC Standards

New Product


Product Image-89358-478

Anti-ATE1 Rabbit Polyclonal Antibody

Description: This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]
Catalog Number: 89358-478
Supplier: Genetex
Image Unavailable-CAAAA11510-36

Iminodiacetic acid 98+%

Description: Inhibitor of bovine liver glutamate dehydrogenase
Catalog Number: CAAAA11510-36
Supplier: Thermo Scientific Chemicals

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