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Catalog Number: (10075-486)
Supplier: Prosci
Description: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.


Catalog Number: (89284-038)
Supplier: Genetex
Description: Rabbit polyclonal antibody to NMDA, NR2C Subunit (phospho Ser1244)


Catalog Number: (89296-882)
Supplier: Genetex
Description: Goat polyclonal antibody to GOT2 (aa 295 to 306)


Catalog Number: (89284-044)
Supplier: Genetex
Description: Rabbit polyclonal antibody to NMDA NR2B Subunit, N-Term


Catalog Number: (89296-932)
Supplier: Genetex
Description: Goat polyclonal antibody to GOT1 (aa 22-35)


Catalog Number: (89276-726)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GluR1 (phospho S849)


Catalog Number: (89273-728)
Supplier: Genetex
Description: Mouse Monoclonal antibody [3G9] to GAD67


Catalog Number: (89296-900)
Supplier: Genetex
Description: Goat polyclonal antibody to GOT1 (aa 157-167)


Catalog Number: (BDH152813W)
Supplier: VWR International
Description: Ion pairing reagent.

Catalog Number: (10349-388)
Supplier: Bioss
Description: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.


Catalog Number: (76081-376)
Supplier: Bioss
Description: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.


Supplier: VWR International
Description: Meets reagent specifications for testing USP/NF monographs.
Catalog Number: (89284-054)
Supplier: Genetex
Description: Rabbit polyclonal antibody to NMDA NR1 Subunit, Splice Variant N1


Catalog Number: (89284-060)
Supplier: Genetex
Description: Rabbit polyclonal antibody to NMDA NR1 Subunit, Splice Variant C1


Catalog Number: (89284-058)
Supplier: Genetex
Description: Rabbit polyclonal antibody to NMDA NR1 Subunit, Splice Variant C2


Supplier: VWR International
Description: AOAC, APHA, and ASTM. Suitable as titrant.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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