You Searched For: 3-Amino-9H-pyrido[3,4-b]indole


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Catalog Number: (10086-496)
Supplier: Proteintech
Description: SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34-kD precursor can be cleaved to produce an active 20-kD product. SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells. Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer.


Supplier: TCI America
Description: CAS Number: 42971-09-5
MDL Number: MFCD00211233
Molecular Formula: C22H26N2O2
Molecular Weight: 350.46
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Melting point (°C): 151
Specific rotation [a]20/D: 118 deg (C=2, Pyridine)
Lambda max.: 315 nm (EtOH)
Catalog Number: (10476-836)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.


Catalog Number: (10476-820)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.


Catalog Number: (10073-130)
Supplier: Prosci
Description: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER) (1). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94 (3,4).


Catalog Number: (89519-602)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89518-784)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89517-214)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89517-444)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (10476-832)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.


Catalog Number: (89518-250)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89519-200)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89519-204)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89516-858)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (89517-646)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (75791-954)
Supplier: Prosci
Description: Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.


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