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Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
Catalog Number: 10481-414
Supplier: Bioss


Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
Catalog Number: 10481-398
Supplier: Bioss


Description: Adhesives, coatings, sealants, inks, thermal insulation, silicones to provide hydrophobicity
Catalog Number: CAAA42783-30
Supplier: Thermo Scientific Chemicals

Description: Air and Emission Standard, Nitrogen Oxide in Impinger Solution, ERA
Catalog Number: CA11022-766
Supplier: ERA


Description: GSSG (Oxidized Glutathione) ELISA Kit
Catalog Number: 77527-512
Supplier: AFG Bioscience


Description: Assay nitric oxide (NO) composition and total as separate values of nitrate (NO3-) and nitrite (NO2-) levels in urine, saliva, plasma, serum and other biological fluids with our Thermo Scientific Nitric Oxide Assay Kit.
Catalog Number: CAPIEMSNOTOT
Supplier: Thermo Scientific

SDS


Description: Viscosity @ 25° 60 cps, pH 3.0, % H2O 1.0
Catalog Number: CAAA43093-A1
Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00011159
Catalog Number: CAAA35671-30
Supplier: Thermo Scientific Chemicals

Description: CAS Number: 1313-13-9
Formula Weight: 86.94
Formula: MnO2
Density (g/mL): 5.0
Freezing Point (°C): 535
Solubility: Hydrochloric Acid
Synonyms: Manganese Dioxide, Manganese Peroxide, Manganese(IV) Oxide
Shelf Life (months): 36
Storage: Yellow
Catalog Number: 470301-728
Supplier: Ward's Science

SDS


Description: CAS Number: 7631-99-4
Formula Weight: 84.99
Formula: NaNO3
Hazard Info: Oxidizer, Explosive, Toxic
Density (g/mL): 2.261
Freezing Point (°C): 307
Solubility: Water and Alcohol
Synonyms: Nitrate of Soda, Chile Saltpeter
Shelf Life (months): 36
Storage: Yellow
Catalog Number: 470302-646
Supplier: Ward's Science

SDS


Description: Silicon(IV) oxide is used in the manufacture of glass for windows, drinking glasses, beverage bottles and many other materials. Optical fibers for telecommunication are made from silica. It is also used as a raw material for many ceramics such as earthenware, stoneware and porcelain. In addition, silica is a common additive in the production of foods and pharmaceutical products.
Catalog Number: CAAA88316-A1
Supplier: Thermo Scientific Chemicals

Description: VWR® Multistage Gas Regulators with Neoprene Diaphragms are designed for applications where a constant working pressure is important over a wide range of inlet pressures and flow rates.
Catalog Number: 55850-494
Supplier: VWR International


Description: MDL: MFCD00011466
Catalog Number: CAAA13398-14
Supplier: Thermo Scientific Chemicals

Description: In 25 mM HEPES, containing 8 µM tetrahydro-L-biopterin, 10% glycerol, pH 7.4. Specific activity: >=7 units/mg protein.
Catalog Number: CA80053-412
Supplier: MilliporeSigma


Description: Suitable for ultraviolet spectrophotometry and liquid chromatography.
Catalog Number: RC9153-32
Supplier: Ricca Chemical

Description: Meets USP Reagent Specifications
Catalog Number: CABJAH340-4
Supplier: Burdick & Jackson

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