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Description: Rabbit monoclonal [EPR26858-4] to Phospho - (Ser/Thr) Phe.

Catalog Number: ABCA_AB300625-100U

Supplier: Abcam

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Description: TEV Protease is a highly specific cysteine protease that recognizes the amino-acid sequence Glu-Asn-Leu-Tyr-Phe-Gln-(Gly/Ser) and cleaves between the Gln and Gly/Ser residues.

Catalog Number: CA76299-648

Supplier: New England Biolabs (NEB)

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Description: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at 'Ser-178' and 'Thr-507' and phosphorylation of CDC25C at 'Ser-216' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at 'Ser-76', 'Ser-124', 'Ser-178', 'Ser-279' and 'Ser-293' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at 'Ser-76' primes the protein for subsequent phosphorylation at 'Ser-79', 'Ser-82' and 'Ser-88' by NEK11, which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at 'Thr-309', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates multiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cellular proliferation. Also promotes repair of DNA cross-links through phosphorylation of FANCE. Binds to and phosphorylates TLK1 at 'Ser-743', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance through regulation of PCNA.

Catalog Number: 10411-694

Supplier: Bioss

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Description: Sequence: H-Ser(tBu)-OMe · HCl

Catalog Number: E-1665.0001BA

Supplier: Bachem Americas

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Description: LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Catalog Number: H-7296.0005BA

Supplier: Bachem Americas

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Description: Required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at 'Ser-178' and 'Thr-507' and phosphorylation of CDC25C at 'Ser-216' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at 'Ser-76', 'Ser-124', 'Ser-178', 'Ser-279' and 'Ser-293' promotes proteolysis of CDC25A. Inhibition of CDC25 activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Binds to and phosphorylates RAD51 at 'Thr-309', which may enhance the association of RAD51 with chromatin and promote DNA repair by homologous recombination. Binds to and phosphorylates TLK1 at 'Ser-743', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may affect chromatin assembly during S phase or DNA repair. May also phosphorylate multiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and enhances suppression of cellular proliferation.

Catalog Number: 10070-040

Supplier: Prosci

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Description: Sequence: Ac-Ser-OMe

Catalog Number: E-1205.0250BA

Supplier: Bachem Americas

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Description:  Human SLAMF7 / CRACC / CD319 Protein, His Tag (Site-specific conjugation), PE-Labeled, Source: expressed from HEK293. It contains AA Ser 23 - Met 226, Predicted N-terminus: Ser 23, protein carries polyhistidine tag at the C-terminus, Synonyms: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12, Size: 25tests

Catalog Number: 103889-084

Supplier: ACROBIOSYSTEMS INC MS

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Description: LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Catalog Number: H-6172.0001BA

Supplier: Bachem Americas

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Description: LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Catalog Number: H-6644.0001BA

Supplier: Bachem Americas

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Description: Anti-Phospho - (Ser/Thr) Phe Rabbit Monoclonal Antibody [clone: EPR26858-4]

Catalog Number: ABCA_AB300626-1MG

Supplier: Abcam

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Description: Human IL-8 protein, His, Avitag*, Biotinylated, Source: expressed from HEK293. It contains AA Ser 28 - Ser 99, Predicted N-terminus: Ser 28, protein carries a polyhistidine tag at C-terminus, followed by an Avi tag, Synonyms: CXCL8, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, Size: 200uG

Catalog Number: 103888-628

Supplier: ACROBIOSYSTEMS INC MS

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Description: Pam₃Cys-Ser-(Lys)₄

Catalog Number: CA80602-584

Supplier: MilliporeSigma

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Description: Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin are found to be involved in the regulation of this protein. Bad is phosphorylated on one or more of Ser-75, Ser-99, Ser-118 and Ser-134 in response to survival stimuli, which blocks its pro-apoptotic activity. Phosphorylation on Ser-99 or Ser-75 promotes heterodimerization with 14-3-3 proteins. This interaction then facilitates the phosphorylation at Ser-118, a site within the BH3 motif, leading to the release of Bcl-X(L) and the promotion of cell survival. Ser-99 is the major site of AKT/PKB phosphorylation, Ser-118 the major site of protein kinase A (CAPK) phosphorylation

Catalog Number: CAPIPA5-12550

Supplier: Thermo Scientific

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Description: Human N-Acetyl-Ser-Asp-Lys-Pro, AcSDKP ELISA Kit

Catalog Number: 76707-870

Supplier: AFG Bioscience

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Description: Mouse N-Acetyl-Ser-Asp-Lys-Pro,AcSDKP ELISA Kit

Catalog Number: 76713-936

Supplier: AFG Bioscience

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