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Catalog Number: (76079-978)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Catalog Number: (10411-186)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Catalog Number: (10351-598)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Catalog Number: (10347-032)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Catalog Number: (10346-586)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.


Catalog Number: (10346-590)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011323 Beilstein Registry No.: 3587158 Fieser: 1,450 2,214 3,154 18,180
Supplier: Thermo Scientific Chemicals
Description: Tellurium tetrabromide, ultra dry ≥99.999% (metals basis)
Catalog Number: (89424-158)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to RUVBL1 (RuvB-like 1 (E. coli))


Catalog Number: (19757-082)
Supplier: Saf-T-Cart
Description: For transporting gas cylinders easily and safely


Catalog Number: (TCN0701-25G)
Supplier: TCI America
Description: CAS Number: 2767-70-6
MDL Number: MFCD00032108
Molecular Formula: C25H21BrNO2P
Molecular Weight: 478.33
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 275

SDS


Supplier: TCI America
Description: Imidazole Hydrobromide (Low water content), Purity: >98.0%(HPLC)(T), CAS number101023-55-6, Molecular Formula: C3H4N2·HBr, Molecular Weight: 148.99, Synonym: Imidazolium Bromide (Low water content), Size: 1G

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00049563
Supplier: Thermo Scientific Chemicals
Description: Bromopentacarbonylmanganese(I) ≥98%
Catalog Number: (CAAA42097-03)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00013295

Supplier: TCI America
Description: 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Bromide, Purity: >98.0%(GC)(T), CAS: 377780-72-8, Molecular Formula: C13H18BBrO2, Molecular Weight: 297.00, Synonym: 2-(Bromomethyl)phenylboronic Acid Pinacol Ester, Size: 5G

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