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Image Unavailable-10479-758

Anti-FAHD2A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: The FAH family contains two highly homologous 314 amino acid proteins, designated FAHD2A (fumarylacetoacetate hydrolase domain-containing protein 2A) and FAHD2B (fumarylacetoacetate hydrolase domain-containing protein 2A). FAHD2A and B utilize calcium and magnesium as cofactors, and may possess hydrolase activity. The genes encoding FAHD2A/B map to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is also associated with mutations to chromosome 2.
Catalog Number: 10479-758
Supplier: Bioss
Image Unavailable-10479-756

Anti-FAHD2A Rabbit Polyclonal Antibody (Cy7®)

Description: The FAH family contains two highly homologous 314 amino acid proteins, designated FAHD2A (fumarylacetoacetate hydrolase domain-containing protein 2A) and FAHD2B (fumarylacetoacetate hydrolase domain-containing protein 2A). FAHD2A and B utilize calcium and magnesium as cofactors, and may possess hydrolase activity. The genes encoding FAHD2A/B map to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is also associated with mutations to chromosome 2.
Catalog Number: 10479-756
Supplier: Bioss
Product Image-CA102902-462

BssSI-v2

Description: An E.coli strain that carries the cloned and modified BssSI gene from Bacillus stearothermophilus S719 (Z. Chen).
Catalog Number: CA102902-462
Supplier: New England Biolabs (NEB)
Image Unavailable-CA607-1502

Anti-IgG Goat Polyclonal Antibody (AP (Alkaline Phosphatase))

Description: Secondary Goat Anti-IgG (H&L) Reacts with Hamster
Catalog Number: CA607-1502
Supplier: Rockland Immunochemical
Product Image-10751-302

Anti-ATP2C2 Rabbit Polyclonal Antibody

Description: ATP2C2 Antibody: ATP2C2, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 2, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in the related gene ATP2C1 cause Hailey-Hailey disease, for which ATP2C2 does not compensate, suggesting that ATP2C2 plays other physiological roles. Unlike ATP2C1, ATP2C2 has a much more restricted expression pattern and displays a higher maximal turnover rate for overall Ca2+-ATPase reaction and a lower apparent affinity for cytosolic Ca2+ activation of phosphorylation. Overexpression of ATP2C2 in mammary tumors result a Ca2+ influx via the store-operated Ca2+ channel ORAI1 and independent of the STIM1 and STIM2 sensors.
Catalog Number: 10751-302
Supplier: Prosci
Image Unavailable-CA80055-586

A23187, Mixed Calcium-Magnesium Salt, Calbiochem

Description: Useful in cell activation experiments when calcium dose-response data are not required.
Catalog Number: CA80055-586
Supplier: MilliporeSigma

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Product Image-CA101444-748

Taq 5X Master Mix, New England Biolabs

Description: Taq 5X Master Mix is an optimized ready-to-use solution containing Taq DNA Polymerase, dNTPs, MgCl2, KCl and stabilizers
Catalog Number: CA101444-748
Supplier: New England Biolabs (NEB)
Image Unavailable-CA602-4503

Anti-IgG Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Description: Secondary Rabbit Anti-IgG F(c) Reacts with Cat (Feline)
Catalog Number: CA602-4503
Supplier: Rockland Immunochemical
Image Unavailable-10487-962

Anti-FIGNL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Catalog Number: 10487-962
Supplier: Bioss
Product Image-CA102902-466

NsiI-HF, Restriction Enzymes, New England Biolabs

Description: NsiI-HF is produced in E. coli from a strain that carries the clone and modified NsiI gene from Neisseria sicca (ATCC 29256).
Catalog Number: CA102902-466
Supplier: New England Biolabs (NEB)
Image Unavailable-CA611-905-002

Anti-IgG Chicken Polyclonal Antibody (AP (Alkaline Phosphatase))

Description: Secondary Chicken Anti-IgG (H&L) Reacts with Rabbit (Lapine)
Catalog Number: CA611-905-002
Supplier: Rockland Immunochemical
Image Unavailable-75977-366

Anti-TOP1MT Mouse Monoclonal Antibody (CF640R) [clone: TOP1MT/488]

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number: 75977-366
Supplier: Biotium
Image Unavailable-10487-964

Anti-FIGNL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Catalog Number: 10487-964
Supplier: Bioss
Image Unavailable-10487-954

Anti-FIGNL1 Rabbit Polyclonal Antibody (Cy3®)

Description: FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Catalog Number: 10487-954
Supplier: Bioss
Image Unavailable-10496-320

Anti-TSSK6 Rabbit Polyclonal Antibody (Cy5.5®)

Description: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
Catalog Number: 10496-320
Supplier: Bioss
Image Unavailable-10496-318

Anti-TSSK6 Rabbit Polyclonal Antibody (Cy5®)

Description: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
Catalog Number: 10496-318
Supplier: Bioss
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