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Catalog Number: (TCB2682-5G)
Supplier: TCI America
Description: CAS Number: 2425-41-4
Molecular Formula: C12H16O4
Molecular Weight: 224.26
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 135

Supplier: CUBE BIOTECH
Description: AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-55 - are highly-alternating copolymers, well-suited for generating native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-55 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general, lighter AASTYs, like 6-55 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.

The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.

Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process, we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022

Supplier: TCI America
Description: CAS Number: 54827-17-7 MDL Number: MFCD00007748 Molecular Formula: C16H20N2 Molecular Weight: 240.35 Purity/Analysis Method: <gt/>98.0% (HPLC,T) Form: Crystal Color: White Melting point (°C): 170
Catalog Number: (TCE0667-1G)
Supplier: TCI America
Description: CAS Number: 346656-34-6
Molecular Formula: C14H19BO4
Molecular Weight: 262.11
Purity/Analysis Method: >98.0% (T)
Form: Clear Liquid
Specific Gravity (20/20): 1.09
Storage Temperature: 0-10°C

Catalog Number: (TCD0894-025G)
Supplier: TCI America
Description: CAS Number: 57-41-0
MDL Number: MFCD00005264
Molecular Formula: C15H12N2O2
Molecular Weight: 252.27
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 298

Catalog Number: (470302-592)
Supplier: Ward's Science
Description: CAS Number: 7681-55-2
Formula Weight: 197.90
Formula: NaIO3
Density (g/mL): 4.277
Solubility: Water, Acetone
Synonyms: Iodic Acid Sodium Salt
Shelf Life (months): 12
Storage: Yellow

SDS


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00801098
Catalog Number: (CA95052-796)
Supplier: Enzo Life Sciences
Description: HRP substrate.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00801098
Catalog Number: (89139-166)
Supplier: Biotium
Description: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.


Supplier: VWR International
Description: Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses and wound healing.

New Product

Supplier: TCI America
Description: CAS Number: 695-53-4
MDL Number: MFCD00005379
Molecular Formula: C5H7NO3
Molecular Weight: 129.12
Purity/Analysis Method: >99.0% (GC,T)
Form: Crystal
Boiling point (°C): 137
Melting point (°C): 79
Supplier: VWR International
Description: Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses.

New Product

Supplier: TCI America
Description: 6,6,7,7,8,8,8-Heptafluoro-5,5-bis(trifluoromethyl)-1,3-octadiene, Purity: >98.0%(GC), CAS No: 1429188-77-1, Molecular Formula: C10H5F13, MW: 372.13, Physical state: Liquid, Form: Clear, Colour: Colorless - Pale yellow, Size: 25G

SDS

Supplier: VWR International
Description: Meets reagent specifications for testing USP/NF monographs.
Catalog Number: (89139-162)
Supplier: Biotium
Description: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.


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