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Image Unavailable-10487-482

Anti-DCAF12 Rabbit Polyclonal Antibody

Description: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR40A (WD-repeat-containing protein 40A), also known as DDB1- CUL4-associated factor 12, is a 453 amino acid cytoplasmic protein that contains four WD-repeats. WDR40A is highly expressed in some cancer cell lines, lung cancer tissues and normal testis. A probable substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex, WRD40A is suggested to interact with DDB1. WDR40A is encoded by a gene mapping to human chromosome 9p13.3. Human chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome.
Catalog Number: 10487-482
Supplier: Bioss
Image Unavailable-TCP0402-500G

Phthalimide ≥98.0% (by GC, titration analysis)

Description: CAS Number: 85-41-6
MDL Number: MFCD00005881
Molecular Formula: C8H5NO2
Molecular Weight: 147.13
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 234
Flash Point (°C): 150
Catalog Number: TCP0402-500G
Supplier: TCI America

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Image Unavailable-10081-412

Anti-PSAP Rabbit Polyclonal Antibody

Description: proteins' (SAPs) that assist in the lysosomal hydrolysis of sphingolipids. After proteolytic processing of the presaposin protein, these 4 released polypeptides are functional activators. Saposin A was encoded by residues 60 to 143 of PSAP, saposin B by 195 to 275, saposin C by 311 to 390, and saposin D by 405 to 487. They are four 12-14 kDa heatstable glycoproteins. This antibody should recognize saposin C.
Catalog Number: 10081-412
Supplier: Proteintech
Image Unavailable-76121-138

Anti-C21orf25 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. C2CD2 is an 696 amino acid protein that is secreted. The C2CD2 gene product has been provisionally designated C2CD2 pending further characterization.
Catalog Number: 76121-138
Supplier: Bioss
Image Unavailable-10081-414

Anti-PSAP Rabbit Polyclonal Antibody

Description: proteins' (SAPs) that assist in the lysosomal hydrolysis of sphingolipids. After proteolytic processing of the presaposin protein, these 4 released polypeptides are functional activators. Saposin A was encoded by residues 60 to 143 of PSAP, saposin B by 195 to 275, saposin C by 311 to 390, and saposin D by 405 to 487. They are four 12-14 kDa heatstable glycoproteins. This antibody should recognize saposin D.
Catalog Number: 10081-414
Supplier: Proteintech
Image Unavailable-75789-656

Human Recombinant CD98 (from Cells)

Description: CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes.
Catalog Number: 75789-656
Supplier: Prosci
Image Unavailable-102981-634

Human Recombinant IL-18 (from E. coli)

Description: Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.
Catalog Number: 102981-634
Supplier: Adipogen
Image Unavailable-10664-344

Anti-KCTD12 Rabbit Polyclonal Antibody

Description: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD12 (potassium channel tetramerisation domain containing 12), also known as PFET1 or PFETIN, is a 325 amino acid protein that is expressed in fetal organs, with highest levels in the cochlea and brain and extremely low levels in adult organs, such as brain and lung. KCTD12 is considered a prognostic biomarker of gastrointestinal stromal tumors.
Catalog Number: 10664-344
Supplier: Bioss
Image Unavailable-TCT1306-005G

N-(Triphenylmethyl)glycine ≥98.0% (by HPLC, titration analysis)

Description: CAS Number: 5893-05-0
MDL Number: MFCD00004276
Molecular Formula: C21H19NO2
Molecular Weight: 317.39
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Catalog Number: TCT1306-005G
Supplier: TCI America

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Image Unavailable-700007-758

L(+)-Glutamine ≥98.5% FCC

Description: L-Glutamine, FCC - The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number: 700007-758
Supplier: Spectrum Chemicals

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Image Unavailable-89359-808

Anti-ACADM Goat Polyclonal Antibody

Description: This protein is a medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.
Catalog Number: 89359-808
Supplier: Genetex
Image Unavailable-10490-698

Anti-DYRK3 Rabbit Polyclonal Antibody (Cy7®)

Description: Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis. Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation. Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases. Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions. Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus. Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland. The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively.
Catalog Number: 10490-698
Supplier: Bioss
Product Image-CAPI20673

N,N-Dimethylformamide ≥99.5%, Sequencing grade, Pierce™

Description: Thermo Scientific Pierce Dimethylformamide (DMF) is a sequencing-grade preparation with high purity and consistent absorptivity properties for use in HPLC and mass spectrometry methods.
Catalog Number: CAPI20673
Supplier: Thermo Scientific

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Image Unavailable-75789-362

Human Recombinant Lumican (from Cells)

Description: Lumican is a 40 kD secreted protein which belongs to the small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily. Human Lumican is synthesized as a 338 amino acid precursor then cut the 18 aa signal sequence. The mature Human Lumican contains 12 leucine-rich repeats (LRRs), 4 potential sites of N-linked glycosylation, and a C- terminal with two conserved cyst-eines. Lumican can be existed in extracellular matrix of human articular cartilage. Lumican participates in the maintenance of tissue homeostasis and regulates cellular functions in vivo, such as cell proliferation, adhesion, migration, and differentiation. The overexpression of lumican has been correlated to colorectal tumor, breast, neuroendocrine, and pancreatic cancers.
Catalog Number: 75789-362
Supplier: Prosci
Image Unavailable-CA-EM4100

EGTA (ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid) ≥97.0%, OmniPur®, Millipore®

Description: For molecular biology. DNase-, RNase-, and protease-free.
Catalog Number: CA-EM4100
Supplier: MilliporeSigma

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Product Image-76076-742

Orion™ Star™ A221 pH Portable Meter, Thermo Scientific

Description: Reliably measure pH, mV, ORP and temperature with the Orion™ Star™ A221 pH Portable Meter for advanced field analysis and printer or computer interfacing.
Catalog Number: 76076-742
Supplier: Thermo Fisher Scientific
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