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Description: Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.
Catalog Number: 10347-618
Supplier: Bioss


Description: Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.
Catalog Number: 10347-632
Supplier: Bioss


Description: CAS Number: 121-39-1
MDL Number: MFCD00005123
Molecular Formula: C11H12O3
Molecular Weight: 192.21
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Boiling point (°C): 152
Flash Point (°C): 113
Specific Gravity (20/20): 1.13
Specific rotation [a]20/D: 0 deg (neat)
Storage Temperature: 0-10°C
Catalog Number: TCE0798-25G
Supplier: TCI America

SDS


Description: ECHS1 functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. ECHS1 is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix.The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.
Catalog Number: 10109-460
Supplier: Prosci


Description: CAS Number: 609-69-8
MDL Number: MFCD02684437
Molecular Formula: C7H12O3
Molecular Weight: 144.17
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 69
Catalog Number: TCH1409-5G
Supplier: TCI America

SDS


Description: Ethyl-3-(trifluoromethyl)crotonate mixture E/Z 96%
Catalog Number: CAAAAL09688-09
Supplier: Thermo Scientific Chemicals

Description: ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Catalog Number: 10109-146
Supplier: Prosci


Description: CAS Number: 13504-85-3
MDL Number: MFCD00037329
Molecular Formula: C13H15NO5
Molecular Weight: 265.27
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 107
Specific rotation [a]20/D: -54 deg (C=2, EtOH)
Catalog Number: TCC2506-25G
Supplier: TCI America

SDS


Description: CAS Number: 94-60-0
MDL Number: MFCD00001460
Molecular Formula: C10H16O4
Molecular Weight: 200.23
Purity/Analysis Method: >92.0% (GC)
Form: Clear Liquid
Boiling point (°C): 263
Flash Point (°C): 94
Freezing point (°C): 13
Catalog Number: TCC1154-500G
Supplier: TCI America

Description: Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.
Catalog Number: 10347-634
Supplier: Bioss


Description: Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of cyclosporin A (CsA) and is encoded by a single unique gene conserved from yeast to humans. Cyclophilin B (CyPB) is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. Cyclophilin D (CyP40) is a widely expressed cytoplasmic protein that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It is a widely expressed cytoplasmic protein.
Catalog Number: 76120-268
Supplier: Bioss


Description: Rtx®-2330 is one of the most polar capillary column stationary phases, and is good for general-purpose applications such as cis/trans FAMEs and dioxin isomers.
Catalog Number: RK10714
Supplier: Restek


Description: High-polarity cyanopropylpolysiloxane column designed for the separation of cis/trans fatty acid methyl esters.
Catalog Number: CAAG112-88A7
Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA


Description: ECHS1 (Enoyl Coenzyme A hydratase, short chain, 1) catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs, in the second step of the mitochondrial fatty acid beta-oxidation pathway.
Catalog Number: 76079-638
Supplier: Bioss


Description: Sequence: H-Hyp-OMe · HCl
Catalog Number: F-1660.0025BA
Supplier: Bachem Americas


Description: ECHS1 functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The protein is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number: 10103-076
Supplier: Prosci


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